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    CG33181 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318916, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG33181provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053181
    Locus tag
    Dmel_CG33181
    See related
    AllianceGenome:FB:FBgn0053181
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1521; CG32714; Dmel\CG33181
    Summary
    Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transport. Predicted to be active in plasma membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in nephronophthisis. Orthologous to several human genes including SLC41A1 (solute carrier family 41 member 1) and SLC41A2 (solute carrier family 41 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33181 in Genome Data Viewer
    Location:
    7F1-7F2; 1-23 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8489348..8517029)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8383381..8411062)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43834 Neighboring gene Chorion protein 38 Neighboring gene ovarian tumor Neighboring gene Neuroglian Neighboring gene PIP82 Neighboring gene Integrator 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functionally Validating Evolutionary Conserved Risk Genes for Parkinson's Disease in Drosophila melanogaster. Baisgaard AE, et al. Insects, 2023 Feb 9. PMID 36835737, Free PMC Article
    2. Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster. Yanagawa A, et al. G3 (Bethesda), 2020 Sep 2. PMID 32727922, Free PMC Article
    3. Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability. Samuels TJ, et al. Elife, 2020 Jan 14. PMID 31934860, Free PMC Article
    4. Glial solute carrier transporters in Drosophila and mice. Featherstone DE. Glia, 2011 Sep. PMID 21732427
    5. The Drosophila blood-brain barrier: development and function of a glial endothelium. Limmer S, et al. Front Neurosci, 2014. PMID 25452710, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables monoatomic cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic cation transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33181-PC
    CG33181-PD
    CG33181-PE
    CG33181-PF
    CG33181-PG
    CG33181-PH
    CG33181-PI
    CG33181-PJ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8489348..8517029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103441.2 → NP_001096911.1  uncharacterized protein Dmel_CG33181, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096911.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV32
      Conserved Domains (1) summary
      pfam01769
      Location:319 → 450
      MgtE; Divalent cation transporter

    2. NM_001272405.1 → NP_001259334.1  uncharacterized protein Dmel_CG33181, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259334.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV32
      Conserved Domains (1) summary
      pfam01769
      Location:319 → 450
      MgtE; Divalent cation transporter

    3. NM_001103438.2 → NP_001096908.1  uncharacterized protein Dmel_CG33181, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096908.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV32
      Conserved Domains (1) summary
      pfam01769
      Location:319 → 450
      MgtE; Divalent cation transporter

    4. NM_001103440.2 → NP_001096910.1  uncharacterized protein Dmel_CG33181, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096910.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV35, I0B8M3
      Conserved Domains (1) summary
      pfam01769
      Location:149 → 280
      MgtE; Divalent cation transporter

    5. NM_001272406.1 → NP_001259335.1  uncharacterized protein Dmel_CG33181, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259335.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PHE6
      Conserved Domains (1) summary
      pfam01769
      Location:293 → 424
      MgtE; Divalent cation transporter

    6. NM_001298093.1 → NP_001285022.1  uncharacterized protein Dmel_CG33181, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285022.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      I0B8M3, X2JE61
      Conserved Domains (1) summary
      pfam01769
      Location:173 → 304
      MgtE; Divalent cation transporter

    7. NM_001103442.2 → NP_001096912.1  uncharacterized protein Dmel_CG33181, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096912.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV32
      Conserved Domains (1) summary
      pfam01769
      Location:319 → 450
      MgtE; Divalent cation transporter

    8. NM_176712.3 → NP_788885.1  uncharacterized protein Dmel_CG33181, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3E3
      Related
      FBpp0112364
      Conserved Domains (1) summary
      pfam01769
      Location:302 → 433
      MgtE; Divalent cation transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JV32 A8JV32
    A8JV35 A8JV35
    M9PHE6 M9PHE6
    Q8SYJ1 Q8SYJ1
    Q9W3E3 Q9W3E3
    X2JE61 X2JE61

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