U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rhp Rhophilin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32531, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rhpprovided by FlyBase
    Official Full Name
    Rhophilinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026374
    Locus tag
    Dmel_CG8497
    See related
    AllianceGenome:FB:FBgn0026374
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8497; Dmel\CG8497
    Summary
    Predicted to be involved in negative regulation of stress fiber assembly. Orthologous to several human genes including RHPN1 (rhophilin Rho GTPase binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rhp in Genome Data Viewer
    Location:
    13E18-13E18; 1-51 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15788897..15793632)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15682930..15687665)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Platelet-activating factor acetylhydrolase alpha Neighboring gene mitochondrial ribosomal protein S30 Neighboring gene suppression of retinal degeneration disease 1 upon overexpression 1 Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    rhophilin
    Names
    CG8497-PA
    CG8497-PB
    Rhp-PA
    Rhp-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15788897..15793632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206724.2NP_996447.1  rhophilin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996447.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXP2, Q9XYY9
      Conserved Domains (3) summary
      cd09244
      Location:122514
      BRO1_Rhophilin; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains
      cd11633
      Location:34118
      HR1_Rhophilin-1; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin-1
      cd00992
      Location:570642
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. NM_078613.4NP_511168.3  rhophilin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_511168.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXP2, Q9XYY9
      Related
      FBpp0073911
      Conserved Domains (3) summary
      cd09244
      Location:122514
      BRO1_Rhophilin; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains
      cd11633
      Location:34118
      HR1_Rhophilin-1; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin-1
      cd00992
      Location:570642
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...