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    Act79B Actin 79B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40444, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Act79Bprovided by FlyBase
    Official Full Name
    Actin 79Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000045
    Locus tag
    Dmel_CG7478
    See related
    AllianceGenome:FB:FBgn0000045
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    143060_f_at; act 79B; ACT4; act79B; actin; Actin; ArpF; CG7478; D; Dmel\CG7478; mus79B
    Summary
    Predicted to be involved in mitotic cytokinesis. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including adult head; adult heart; adult somatic muscle cell; male genitalia; and scutellar pulsatile organ. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome 1 and thrombocytopenia. Orthologous to human ACTB (actin beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Act79B in Genome Data Viewer
    Location:
    79A6-79A6; 3-47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21985210..21987190)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21978310..21980290)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Chitin synthase 2 Neighboring gene Delta[1]-pyrroline-5-carboxylate synthase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental expression of a Drosophila actin gene encoding actin I. Zulauf E, et al. Nature, 1981 Aug 6. PMID 6789212
    2. Absence of the Drosophila jump muscle actin Act79B is compensated by up-regulation of Act88F. Dohn TE, et al. Dev Dyn, 2018 Apr. PMID 29318731, Free PMC Article
    3. Evolution of a neuromuscular sexual dimorphism in the Drosophila montium species group. Liang HQ, et al. Sci Rep, 2021 Jul 27. PMID 34315982, Free PMC Article
    4. Two Drosophila actin genes in detail. Gene structure, protein structure and transcription during development. Sanchez F, et al. J Mol Biol, 1983 Feb 5. PMID 6405041
    5. Tissue-specific expression of the 79B actin gene during Drosophila development. Courchesne-Smith CL, et al. Dev Biol, 1989 Jun. PMID 2499492

    See all (150) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling.
      Title: Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling.
    2. TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis.
      Title: TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    actin 79B
    Names
    79B actin
    Act79B-PA
    Act79B-PB
    CG7478-PA
    CG7478-PB
    F-actin
    actin
    actin-79B

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21985210..21987190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275271.1 → NP_001262200.1  actin 79B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262200.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02574, Q540X7, Q9VNW5
      UniProtKB/TrEMBL
      C6TP14, M9PFZ6
      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional

    2. NM_079486.4 → NP_524210.1  actin 79B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524210.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02574, Q540X7, Q9VNW5
      UniProtKB/TrEMBL
      C6TP14, M9PFZ6
      Related
      FBpp0078131
      Conserved Domains (1) summary
      PTZ00281
      Location:1 → 376
      PTZ00281; actin; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PFZ6 M9PFZ6
    P02574.2 P02574

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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