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    MFS15 Major Facilitator Superfamily Transporter 15 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37168, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MFS15provided by FlyBase
    Official Full Name
    Major Facilitator Superfamily Transporter 15provided by FlyBase
    Primary source
    FLYBASE:FBgn0034392
    Locus tag
    Dmel_CG15094
    See related
    AllianceGenome:FB:FBgn0034392
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15094; Dmel\CG15094
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. Is expressed in several structures, including adult head; amnioserosa; embryonic/larval salivary gland; plasmatocyte primordium; and salivary gland body primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See MFS15 in Genome Data Viewer
    Location:
    55F3-55F3; 2-86 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18794618..18796678, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14682123..14684183, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43964 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Major Facilitator Superfamily Transporter 14 Neighboring gene long non-coding RNA:CR44468

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Embryonic expression patterns of Drosophila ACS family genes related to the human sialin gene. Laridon B, et al. Gene Expr Patterns, 2008 Apr. PMID 18255354
    2. Organ-specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA. Fox RM, et al. Development, 2013 May. PMID 23578928, Free PMC Article
    3. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
    4. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
    5. Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. Vinci G, et al. PLoS One, 2008 Aug 6. PMID 18682733, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    major facilitator superfamily transporter 15
    Names
    CG15094-PA
    CG15094-PB
    MFS15-PA
    MFS15-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18794618..18796678 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137531.2 → NP_611375.2  major facilitator superfamily transporter 15, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611375.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBD9, Q6NR28
      Related
      FBpp0085818
      Conserved Domains (2) summary
      cd06174
      Location:31 → 459
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:18 → 469
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    2. NM_166308.2 → NP_725828.1  major facilitator superfamily transporter 15, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBE0, Q6NR28
      Related
      FBpp0085819
      Conserved Domains (2) summary
      cd06174
      Location:13 → 405
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:13 → 368
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBD9 A1ZBD9
    A1ZBE0 A1ZBE0
    Q6NR28 Q6NR28

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