Zfp120 zinc finger protein 120 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp120provided by MGI
Official Full Name: zinc finger protein 120provided by MGI
Primary source: MGI:MGI:1345179
See related: Ensembl:ENSMUSG00000068134 AllianceGenome:MGI:1345179
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: F80; MZF31; Zfp844; E030042N05Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; eye; and genitourinary system. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in bladder adult (RPKM 1.4), CNS E18 (RPKM 1.2) and 24 other tissues See more
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Genomic context

Location:: 2 G3; 2 74.0 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (149956327..149978598, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (150114407..150136678, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:234550

BB225009 (e-PCR)
- UniSTS:207423

AI315103 (e-PCR)
- UniSTS:159048

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein 120

Names: zinc finger protein 31; zinc finger protein 844

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_023266.4 → NP_075755.4 zinc finger protein 120 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

AF211869, AK033399, AK132318

Consensus CDS

CCDS38264.1

UniProtKB/TrEMBL

A2ANU5, Q9EQK2

Related

ENSMUSP00000105557.2, ENSMUST00000109931.8

Conserved Domains (2) summary

smart00349
Location:28 → 68

KRAB; krueppel associated box

pfam01352
Location:28 → 67

KRAB; KRAB box
NM_181266.2 → NP_851783.2 zinc finger protein 120 isoform 1 precursor

See identical proteins and their annotated locations for NP_851783.2

Status: VALIDATED

Source sequence(s)

AK033399, AK132318

Consensus CDS

CCDS38263.1

UniProtKB/Swiss-Prot

Q78JR8, Q8BZW4, Q9EQK4, Q9JIB8

Related

ENSMUSP00000086615.7, ENSMUST00000089207.13

Conserved Domains (5) summary

smart00349
Location:28 → 69

KRAB; krueppel associated box

COG5048
Location:140 → 387

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:298 → 318

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:28 → 67

KRAB; KRAB box

pfam13465
Location:338 → 363

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000068.8 Reference GRCm39 C57BL/6J

Range

149956327..149978598 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_181267.2: Suppressed sequence

Description

NM_181267.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.