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    Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 [ Mus musculus (house mouse) ]

    Gene ID: 16516, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Kcnj15provided by MGI
    Official Full Name
    potassium inwardly-rectifying channel, subfamily J, member 15provided by MGI
    Primary source
    MGI:MGI:1310000
    See related
    Ensembl:ENSMUSG00000062609 AllianceGenome:MGI:1310000
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IRKK; Kir4.2; 4930414N08Rik
    Summary
    Enables potassium channel activity. Acts upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to human KCNJ15 (potassium inwardly rectifying channel subfamily J member 15). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in kidney adult (RPKM 32.3), lung adult (RPKM 4.3) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Kcnj15 in Genome Data Viewer
    Location:
    16 C4; 16 55.86 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (95058417..95101119)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (95257558..95300260)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_41599 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene predicted gene, 31641 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:95484660-95484843 Neighboring gene predicted gene, 31754 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95563080-95563380 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95572113-95572413 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95581838-95582139 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95649181-95649482 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95650074-95650374 Neighboring gene ETS transcription factor Neighboring gene STARR-seq mESC enhancer starr_41600 Neighboring gene STARR-seq mESC enhancer starr_41602 Neighboring gene predicted gene, 31845

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2. Zhang Y, et al. Nat Commun, 2024 Jun 17. PMID 38886379, Free PMC Article
    2. Kir4.2 mediates proximal potassium effects on glutaminase activity and kidney injury. Terker AS, et al. Cell Rep, 2022 Dec 20. PMID 36543132, Free PMC Article
    3. Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion. Bignon Y, et al. Kidney Int, 2020 Feb. PMID 31870500
    4. Developmentally regulated expression of the murine ortholog of the potassium channel KIR4.2 (KCNJ15). Thiery E, et al. Mech Dev, 2000 Jul. PMID 10906485
    5. Acid secretion-associated translocation of KCNJ15 in gastric parietal cells. He W, et al. Am J Physiol Gastrointest Liver Physiol, 2011 Oct. PMID 21719736, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na[+] Channel (ENaC).
      Title: Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na(+) Channel (ENaC).
    2. Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.
      Title: Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.
    3. Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion.
      Title: Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion.
    4. Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.
      Title: Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice.
    5. It was shown that downregulation of Kcnj15 leads to increased insulin secretion in vitro and in vivo. The mechanism for regulating insulin secretion inolved a calcium-sensiong receptor.
      Title: Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.
    6. in nonsecreting parietal cells, KCNJ15 is stored in vesicles distinct from the H(+)-K(+)-ATPase-enriched tubulovesicles. Furthermore, upon stimulation, KCNJ15 and H(+)-K(+)-ATPase both translocate to the apical membrane for active acid secretion.
      Title: Acid secretion-associated translocation of KCNJ15 in gastric parietal cells.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables inward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inward rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inward rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables potassium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within potassium ion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of monoatomic ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ATP-sensitive inward rectifier potassium channel 15
    Names
    inward rectifier K+ channel Kir4.2
    potassium channel, inwardly rectifying subfamily J member 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039056.2 → NP_001034145.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_001034145.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154691, AK165436
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Related
      ENSMUSP00000109485.2, ENSMUST00000113854.8
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    2. NM_001039057.2 → NP_001034146.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

      See identical proteins and their annotated locations for NP_001034146.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
      Source sequence(s)
      AC154691, AI116801, AK165436
      Consensus CDS
      CCDS28351.1
      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Related
      ENSMUSP00000045218.8, ENSMUST00000037154.14
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    3. NM_001271687.1 → NP_001258616.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

      See identical proteins and their annotated locations for NP_001258616.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
      Source sequence(s)
      AC154691, AI891955, AK165436
      Consensus CDS
      CCDS28351.1
      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    4. NM_001271689.1 → NP_001258618.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_001258618.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154546, AC154691
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Related
      ENSMUSP00000109486.2, ENSMUST00000113855.8
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    5. NM_001271690.1 → NP_001258619.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

      See identical proteins and their annotated locations for NP_001258619.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
      Source sequence(s)
      AC154691, AK165346, AK165436
      Consensus CDS
      CCDS28351.1
      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Related
      ENSMUSP00000109492.2, ENSMUST00000113861.8
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    6. NM_001271691.1 → NP_001258620.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_001258620.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154691, AK165436, AW012236
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    7. NM_001271692.1 → NP_001258621.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

      See identical proteins and their annotated locations for NP_001258621.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
      Source sequence(s)
      AC154546, AC154691
      Consensus CDS
      CCDS28351.1
      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    8. NM_001271693.1 → NP_001258622.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_001258622.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154691, AK165436, AW258994, AY377988
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    9. NM_001271694.1 → NP_001258623.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

      See identical proteins and their annotated locations for NP_001258623.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
      Source sequence(s)
      AC154691, AK165436, AW319416
      Consensus CDS
      CCDS28351.1
      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    10. NM_001271695.1 → NP_001258624.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_001258624.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154691, AI891955, AK165436, BB843850
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    11. NM_019664.5 → NP_062638.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

      See identical proteins and their annotated locations for NP_062638.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
      Source sequence(s)
      AC154691, AK165436, AW260030, AY377988
      Consensus CDS
      CCDS37410.1
      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Related
      ENSMUSP00000109487.2, ENSMUST00000113856.8
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    RNA

    1. NR_073406.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) uses an alternate splice site and two alternate internal exons, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC154546, AC154691

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      95058417..95101119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522944.3 → XP_006523007.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      See identical proteins and their annotated locations for XP_006523007.1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Related
      ENSMUSP00000109493.2, ENSMUST00000113862.8
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    2. XM_006522951.4 → XP_006523014.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

      See identical proteins and their annotated locations for XP_006523014.1

      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    3. XM_006522942.4 → XP_006523005.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      See identical proteins and their annotated locations for XP_006523005.1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    4. XM_006522950.4 → XP_006523013.1  ATP-sensitive inward rectifier potassium channel 15 isoform X2

      See identical proteins and their annotated locations for XP_006523013.1

      UniProtKB/TrEMBL
      Q3TR79
      Conserved Domains (2) summary
      pfam01007
      Location:46 → 187
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:194 → 365
      IRK_C; Inward rectifier potassium channel C-terminal domain

    5. XM_006522945.4 → XP_006523008.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      See identical proteins and their annotated locations for XP_006523008.1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    6. XM_017316883.2 → XP_017172372.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Related
      ENSMUSP00000109490.2, ENSMUST00000113859.8
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    7. XM_017316885.1 → XP_017172374.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Related
      ENSMUSP00000109489.3, ENSMUST00000113858.3
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain

    8. XM_036159796.1 → XP_036015689.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    9. XM_017316884.1 → XP_017172373.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    10. XM_006522947.3 → XP_006523010.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      See identical proteins and their annotated locations for XP_006523010.1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    11. XM_006522946.4 → XP_006523009.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

      See identical proteins and their annotated locations for XP_006523009.1

      UniProtKB/TrEMBL
      B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
      Conserved Domains (2) summary
      pfam01007
      Location:57 → 198
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:205 → 376
      IRK_C; Inward rectifier potassium channel C-terminal domain

    12. XM_006522952.5 → XP_006523015.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

      See identical proteins and their annotated locations for XP_006523015.1

      UniProtKB/Swiss-Prot
      O88932, Q9JK34
      UniProtKB/TrEMBL
      Q3TR79, Q53Z04
      Conserved Domains (2) summary
      pfam01007
      Location:30 → 171
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:178 → 349
      IRK_C; Inward rectifier potassium channel C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O88932.1 GenPept UniProtKB/Swiss-Prot:O88932

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