U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG8814 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33492, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG8814provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031478
    Locus tag
    Dmel_CG8814
    See related
    AllianceGenome:FB:FBgn0031478
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    DmCG8814; Dmel\CG8814
    Summary
    Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. Predicted to be active in cytoplasm. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in retinal dystrophy with leukodystrophy. Orthologous to several human genes including ACBD5 (acyl-CoA binding domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG8814 in Genome Data Viewer
    Location:
    23B8-23C1; 2-8 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2874890..2877168)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2874890..2877168)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Interferon-related developmental regulator 1 Neighboring gene uncharacterized protein Neighboring gene Peroxiredoxin 6a Neighboring gene Rab geranylgeranyltransferase subunit beta Neighboring gene Sabbat Neighboring gene NTPase

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The ACBP gene family in Rhodnius prolixus: Expression, characterization and function of RpACBP-1. Majerowicz D, et al. Insect Biochem Mol Biol, 2016 May. PMID 27001070
    2. Monitoring lipid alterations in Drosophila heads in an amyotrophic lateral sclerosis model with time-of-flight secondary ion mass spectrometry. Le MUT, et al. Analyst, 2024 Jan 29. PMID 38167886
    3. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster. Dembeck LM, et al. Elife, 2015 Nov 14. PMID 26568309, Free PMC Article
    4. EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel. Gaspar CJ, et al. EMBO Rep, 2022 Jan 5. PMID 34918864, Free PMC Article
    5. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG8814-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2874890..2877168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134885.4 → NP_608729.1  uncharacterized protein Dmel_CG8814 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608729.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQI6
      Related
      FBpp0077314
      Conserved Domains (2) summary
      pfam00887
      Location:5 → 90
      ACBP; Acyl CoA binding protein
      pfam07889
      Location:217 → 272
      DUF1664; Protein of unknown function (DUF1664)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQI6 Q9VQI6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous