U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG3927 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37576, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG3927provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034739
    Locus tag
    Dmel_CG3927
    See related
    AllianceGenome:FB:FBgn0034739
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT29209; cg3927; Dmel\CG3927
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut; embryonic/larval midgut primordium; and posterior endoderm. Orthologous to human KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG3927 in Genome Data Viewer
    Location:
    58F1-58F1; 2-100 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22594677..22596348)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18482182..18483853)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene defense repressor 1 Neighboring gene long non-coding RNA:CR45328 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Testis-Specific Bb8 Is Essential in the Development of Spermatid Mitochondria. Vedelek V, et al. PLoS One, 2016. PMID 27529784, Free PMC Article
    2. The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis. Vedelek V, et al. Sci Rep, 2021 Apr 19. PMID 33875704, Free PMC Article
    3. The mapping of Drosophila melanogaster mutant A.4.4. Bieser K, et al. MicroPubl Biol, 2018 Dec 17. PMID 32550366, Free PMC Article
    4. A young Drosophila duplicate gene plays essential roles in spermatogenesis by regulating several Y-linked male fertility genes. Ding Y, et al. PLoS Genet, 2010 Dec 23. PMID 21203494, Free PMC Article
    5. Determination of gene expression patterns using in situ hybridization to Drosophila testes. Morris CA, et al. Nat Protoc, 2009. PMID 20010932

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG3927-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22594677..22596348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137837.2 → NP_611681.1  uncharacterized protein Dmel_CG3927 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611681.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8U7, Q9W240
      Related
      FBpp0071764
      Conserved Domains (1) summary
      cd02395
      Location:83 → 201
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T8U7 Q8T8U7
    Q9W240 Q9W240

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous