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    RpL18A Ribosomal protein L18A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36985, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL18Aprovided by FlyBase
    Official Full Name
    Ribosomal protein L18Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010409
    Locus tag
    Dmel_CG6510
    See related
    AllianceGenome:FB:FBgn0010409
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey75; CG6510; Dmel\CG6510; L18; L18a; L18A; L20e; Rpl18A; RpL18a; RPL18a
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Orthologous to human RPL18A (ribosomal protein L18a). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL18A in Genome Data Viewer
    Location:
    54C3-54C3; 2-83 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17546406..17547462, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13433911..13434967, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Coiled-coil and C2 domain containing 2A Neighboring gene uncharacterized protein Neighboring gene cyclophilin-33 Neighboring gene Misexpression suppressor of ras 4 Neighboring gene Kinesin-like protein at 54D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila ribosomal protein L18a: cDNA sequence, expression and chromosomal localization of the gene. Ntwasa M, et al. Biochim Biophys Acta, 1994 Jun 21. PMID 8018724
    2. A new family of cyclophilins with an RNA recognition motif that interact with members of the trx/MLL protein family in Drosophila and human cells. Anderson M, et al. Dev Genes Evol, 2002 Apr. PMID 11976948
    3. Structural and functional diversity of lysyl oxidase and the LOX-like proteins. Molnar J, et al. Biochim Biophys Acta, 2003 Apr 11. PMID 12686136
    4. Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activity. Pinnola A, et al. J Biol Chem, 2007 Nov 2. PMID 17827147
    5. Ribosome components are associated with sites of transcription. Brogna S, et al. Mol Cell, 2002 Jul. PMID 12150910

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L18A
    Names
    CG6510-PA
    RpL18A-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17546406..17547462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079050.3 → NP_523774.1  ribosomal protein L18A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523774.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41093, Q9V840
      Related
      FBpp0086103
      Conserved Domains (1) summary
      COG2157
      Location:69 → 153
      RPL20A; Ribosomal protein L20A (L18A) [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41093.1 P41093

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