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    RpL13A Ribosomal protein L13A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40687, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL13Aprovided by FlyBase
    Official Full Name
    Ribosomal protein L13Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037351
    Locus tag
    Dmel_CG1475
    See related
    AllianceGenome:FB:FBgn0037351
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe1A5; anon-EST:Posey125; bs25f04.y1; cg1475; CG1475; chr3R:1451210..1451407; Dmel\CG1475; L13; L13A; L13a2; M(3)83B; Rp L13A; RpL13; Rpl13a; RpL13a; RPL13A
    Summary
    A structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Located in cytosolic ribosome. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gut section; larval muscle cell; and mesoderm. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL13A in Genome Data Viewer
    Location:
    83B6-83B7; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5624474..5625947)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1450196..1451669)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46135 Neighboring gene Another transcription unit Neighboring gene Spec2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Diphthamide biosynthesis 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress. Huang K, et al. BMC Genomics, 2019 Jan 16. PMID 30651069, Free PMC Article
    2. Parental allele-specific protein expression in single cells In vivo. Lo CA, et al. Dev Biol, 2019 Oct 1. PMID 31194972
    3. Anchor Away: A System for Fast Inhibition of Proteins in Drosophila. Sanchez Bosch P. Methods Mol Biol, 2022. PMID 35980581
    4. Quantification of Protein Levels in Single Living Cells. Lo CA, et al. Cell Rep, 2015 Dec 22. PMID 26686644
    5. tRNA-derived small RNAs are embedded in the gene regulatory network instructing Drosophila metamorphosis. Shi J, et al. Genome Res, 2023 Dec 27. PMID 37973194, Free PMC Article

    See all (81) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L13A
    Names
    60S ribosomal protein L13A
    CG1475-PB
    CG1475-PC
    RpL13A-PB
    RpL13A-PC
    anon-fast-evolving-1A5
    ribosomal protein L13a

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5624474..5625947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275362.1 → NP_001262291.1  ribosomal protein L13A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262291.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFM7
      Conserved Domains (1) summary
      cl00333
      Location:6 → 88
      Ribosomal_L13; Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the ...

    2. NM_141303.3 → NP_649560.1  ribosomal protein L13A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649560.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VNE9, Q9VNF0
      Related
      FBpp0078354
      Conserved Domains (1) summary
      cl00333
      Location:6 → 203
      Ribosomal_L13; Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFM7 A0A0B4KFM7
    Q9VNE9.1 Q9VNE9

    Gene LinkOut

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