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    CG14877 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41929, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG14877provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038380
    Locus tag
    Dmel_CG14877
    See related
    AllianceGenome:FB:FBgn0038380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14877; DrGC-2; Gyc89A
    Summary
    Predicted to enable natriuretic peptide receptor activity and peptide hormone binding activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG14877 in Genome Data Viewer
    Location:
    89A7-89A8; 3-58 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15889194..15896078, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11714916..11721800, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heavy metal tolerance factor 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene globin 1 Neighboring gene pseudo

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables natriuretic peptide receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables peptide hormone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG14877-PA
    guanylyl cyclase at 89A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15889194..15896078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142250.2NP_650507.1  uncharacterized protein Dmel_CG14877 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650507.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VF16
      Related
      FBpp0082703
      Conserved Domains (1) summary
      cl10011
      Location:46241
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily