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    S1PR2 sphingosine-1-phosphate receptor 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 540305, updated on 30-Jan-2025

    Summary

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    Official Symbol
    S1PR2provided by VGNC
    Official Full Name
    sphingosine-1-phosphate receptor 2provided by VGNC
    Primary source
    VGNC:VGNC:34253
    See related
    BGD:BT21757; EnsemblRapid:ENSBTAG00070014165
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    EDG5
    Orthologs
    human mouse all
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    Genomic context

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    See S1PR2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (14748494..14756256, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit G Neighboring gene DNA methyltransferase 1 Neighboring gene microRNA mir-2454 Neighboring gene U6 spliceosomal RNA Neighboring gene mitochondrial ribosomal protein L4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC155267

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingosine-1-phosphate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine-1-phosphate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine 1-phosphate receptor 2
    Names
    endothelial differentiation, sphingolipid G-protein-coupled receptor, 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081541.1 → NP_001075010.1  sphingosine 1-phosphate receptor 2

      See identical proteins and their annotated locations for NP_001075010.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133422
      UniProtKB/TrEMBL
      A0AAA9TQW4, A2VDV6
      Related
      ENSBTAP00070018833.1, ENSBTAT00070032129.1
      Conserved Domains (2) summary
      cd14964
      Location:36 → 60
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:34 → 299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14748494..14756256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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