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    PRUNE1 prune exopolyphosphatase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 524973, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PRUNE1provided by VGNC
    Official Full Name
    prune exopolyphosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:33428
    See related
    BGD:BT14732; Ensembl:ENSBTAG00000015336
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PRUNE
    Orthologs
    human mouse all
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    Genomic context

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    See PRUNE1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (19746347..19766190, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C1orf56 homolog Neighboring gene BCL2 interacting protein like Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene MINDY lysine 48 deubiquitinase 1 Neighboring gene annexin A9 Neighboring gene ceramide synthase 2 Neighboring gene SET domain bifurcated histone lysine methyltransferase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables exopolyphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    exopolyphosphatase PRUNE1
    Names
    protein prune homolog
    prune homolog
    NP_001030429.1
    XP_010801331.1
    XP_015318194.1
    XP_024845139.2
    XP_024845140.1
    XP_059740569.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035352.1 → NP_001030429.1  exopolyphosphatase PRUNE1

      See identical proteins and their annotated locations for NP_001030429.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020783
      UniProtKB/Swiss-Prot
      Q5E9Y6
      UniProtKB/TrEMBL
      A0A3Q1LY96
      Conserved Domains (2) summary
      COG1227
      Location:21 → 361
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam02833
      Location:218 → 357
      DHHA2; DHHA2 domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19746347..19766190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010803029.4 → XP_010801331.1  exopolyphosphatase PRUNE1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LY96
      Related
      ENSBTAP00000062223.2, ENSBTAT00000078005.2
      Conserved Domains (2) summary
      pfam02833
      Location:185 → 327
      DHHA2; DHHA2 domain
      cl27346
      Location:66 → 254
      DHHA2; DHHA2 domain

    2. XM_015462708.3 → XP_015318194.1  exopolyphosphatase PRUNE1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LY96, A0AAA9SH02
      Related
      ENSBTAP00000085481.1, ENSBTAT00000103669.1
      Conserved Domains (2) summary
      COG1227
      Location:21 → 253
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam02833
      Location:218 → 304
      DHHA2; DHHA2 domain

    3. XM_024989372.2 → XP_024845140.1  exopolyphosphatase PRUNE1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LY96
      Conserved Domains (2) summary
      COG1227
      Location:26 → 258
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam02833
      Location:221 → 310
      DHHA2; DHHA2 domain

    4. XM_024989371.2 → XP_024845139.2  exopolyphosphatase PRUNE1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LY96, A0AAF6Z1D5
      Related
      ENSBTAP00000020388.5, ENSBTAT00000020388.6

    5. XM_059884586.1 → XP_059740569.1  exopolyphosphatase PRUNE1 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E9Y6.1 GenPept UniProtKB/Swiss-Prot:Q5E9Y6

    Gene LinkOut

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