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    PREP prolyl endopeptidase [ Bos taurus (domestic cattle) ]

    Gene ID: 286818, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PREPprovided by VGNC
    Official Full Name
    prolyl endopeptidaseprovided by VGNC
    Primary source
    VGNC:VGNC:33310
    See related
    BGD:BT20501; Ensembl:ENSBTAG00000016281
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PREP in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (44576174..44708317)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346107 Neighboring gene small ribosomal subunit protein eS25-like Neighboring gene HIG1 domain family member 1A, mitochondrial-like Neighboring gene popeye domain containing 3 Neighboring gene uncharacterized LOC112448050 Neighboring gene blood vessel epicardial substance

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Cloning and expression of the cDNA encoding prolyl oligopeptidase (prolyl endopeptidase) from bovine brain. Yoshimoto T, et al. Biol Pharm Bull, 1997 Oct. PMID 9353562
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139175

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oligopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prolyl endopeptidase
    Names
    PE
    post-proline cleaving enzyme
    prolyl oligopeptidase
    NP_777197.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174772.1 → NP_777197.1  prolyl endopeptidase

      See identical proteins and their annotated locations for NP_777197.1

      Status: PROVISIONAL

      Source sequence(s)
      AB028866
      UniProtKB/Swiss-Prot
      Q9XTA2
      UniProtKB/TrEMBL
      A5D7C6
      Related
      ENSBTAP00000065243.1, ENSBTAT00000077452.1
      Conserved Domains (2) summary
      COG1505
      Location:26 → 704
      PreP; Prolyl oligopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism]
      pfam00326
      Location:488 → 707
      Peptidase_S9; Prolyl oligopeptidase family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      44576174..44708317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XTA2.1 GenPept UniProtKB/Swiss-Prot:Q9XTA2

    Gene LinkOut

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