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    TRIM36 tripartite motif containing 36 [ Bos taurus (domestic cattle) ]

    Gene ID: 539023, updated on 1-Jan-2025

    Summary

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    Official Symbol
    TRIM36provided by VGNC
    Official Full Name
    tripartite motif containing 36provided by VGNC
    Primary source
    VGNC:VGNC:36331
    See related
    Ensembl:ENSBTAG00000014027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM36 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (3972433..4015587, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S17 pseudogene Neighboring gene GTP-binding nuclear protein Ran-like Neighboring gene protein geranylgeranyltransferase type I subunit beta Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene coiled-coil domain containing 112

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acrosome reaction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in acrosomal vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM36
    NP_001193655.1
    XP_024853490.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206726.2 → NP_001193655.1  E3 ubiquitin-protein ligase TRIM36

      Status: VALIDATED

      Source sequence(s)
      NKLS02000010
      UniProtKB/TrEMBL
      A0A3Q1N3G7, A0AAA9T8U3
      Related
      ENSBTAP00000064051.1, ENSBTAT00000085179.1
      Conserved Domains (5) summary
      smart00060
      Location:431 → 492
      FN3; Fibronectin type 3 domain
      cd00021
      Location:211 → 249
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      pfam13445
      Location:33 → 61
      zf-RING_UBOX; RING-type zinc-finger
      cd12894
      Location:516 → 719
      SPRY_PRY_TRIM36; PRY/SPRY domain in tripartite motif-containing protein 36 (TRIM36)
      cl23765
      Location:256 → 380
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      3972433..4015587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024997722.2 → XP_024853490.1  E3 ubiquitin-protein ligase TRIM36 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SX03, A0AAA9T8U3
      Related
      ENSBTAP00000089849.1, ENSBTAT00000105009.1
      Conserved Domains (5) summary
      smart00060
      Location:419 → 480
      FN3; Fibronectin type 3 domain
      cd00021
      Location:199 → 237
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd12894
      Location:504 → 707
      SPRY_PRY_TRIM36; PRY/SPRY domain in tripartite motif-containing protein 36 (TRIM36)
      cd16756
      Location:16 → 113
      RING-HC_TRIM36; RING finger, HC subclass, found in tripartite motif-containing protein 36 (TRIM36) and similar proteins
      cl25407
      Location:244 → 368
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials