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    IL10RA interleukin 10 receptor subunit alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 513478, updated on 1-Jan-2025

    Summary

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    Official Symbol
    IL10RAprovided by VGNC
    Official Full Name
    interleukin 10 receptor subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:30107
    See related
    BGD:BT10626; Ensembl:ENSBTAG00000005215
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See IL10RA in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (28659617..28673033)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342317 Neighboring gene FXYD domain containing ion transport regulator 6 Neighboring gene transmembrane serine protease 13 Neighboring gene small integral membrane protein 35 Neighboring gene small nucleolar RNA SNORA40 Neighboring gene transmembrane serine protease 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9. Mallikarjunappa S, et al. BMC Genet, 2020 Nov 2. PMID 33138773, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9.
      Title: Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables interleukin-10 receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-10 receptor subunit alpha
    Names
    interleukin 10 receptor, alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205757.2 → NP_001192686.1  interleukin-10 receptor subunit alpha precursor

      See identical proteins and their annotated locations for NP_001192686.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000015
      Conserved Domains (1) summary
      pfam01108
      Location:27 → 117
      Tissue_fac; Tissue factor

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28659617..28673033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215831.5 → XP_005215888.1  interleukin-10 receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      F1MM48
      Related
      ENSBTAP00000006870.5, ENSBTAT00000006870.6
      Conserved Domains (1) summary
      pfam01108
      Location:21 → 113
      Tissue_fac; Tissue factor

    2. XM_024975214.2 → XP_024830982.1  interleukin-10 receptor subunit alpha isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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