These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001038035.3 → NP_001033124.2  protein FAM118A isoform 1

   See identical proteins and their annotated locations for NP_001033124.2

   Status: VALIDATED

   Description

   Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

   Source sequence(s)

   NKLS02000005

   UniProtKB/TrEMBL

   A0AAF6DM31

   Conserved Domains (1) summary

   pfam13289
   Location:142 → 247

   SIR2_2; SIR2-like domain

2. NM_001314066.1 → NP_001300995.1  protein FAM118A isoform 2

   Status: VALIDATED

   Description

   Transcript Variant: This variant (2) differs in the 3' UTR and uses an alternate splice site in the 3' coding region, resulting in a novel 3' coding region compared to variant 1. The encoded isoform (2) has a distinct C-terminus, and is shorter than isoform 1.

   Source sequence(s)

   BC111196

   UniProtKB/TrEMBL

   A0AAF6DM31, F6S145, Q2T9Z4

   Conserved Domains (1) summary

   pfam13289
   Location:142 → 247

   SIR2_2; SIR2-like domain

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference ARS-UCD2.0 Primary Assembly

Genomic

1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

   Range

   115709690..115732868

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_059886176.1 → XP_059742159.1  protein FAM118A isoform X1

   UniProtKB/TrEMBL

   A0A3Q1LRB4, A0AAF6DM31

2. XM_024991452.2 → XP_024847220.1  protein FAM118A isoform X1

   UniProtKB/TrEMBL

   A0A3Q1LRB4, A0AAF6DM31

   Related

   ENSBTAP00070011312.1, ENSBTAT00070019075.1

   Conserved Domains (1) summary

   pfam13289
   Location:143 → 248

   SIR2_2; SIR2-like domain

3. XM_059886177.1 → XP_059742160.1  protein FAM118A isoform X3

   UniProtKB/TrEMBL

   A0AAF6DM31

4. XM_059886179.1 → XP_059742162.1  protein FAM118A isoform X5

   UniProtKB/TrEMBL

   A0AAF6DM31

5. XM_024991456.2 → XP_024847224.1  protein FAM118A isoform X2

   UniProtKB/TrEMBL

   A0AAF6DM31

   Related

   ENSBTAP00070011307.1, ENSBTAT00070019063.1

   Conserved Domains (1) summary

   pfam13289
   Location:142 → 247

   SIR2_2; SIR2-like domain

6. XM_059886178.1 → XP_059742161.1  protein FAM118A isoform X4

   UniProtKB/TrEMBL

   A0AAF6DM31, F6S145, Q2T9Z4

7. XM_024991454.2 → XP_024847222.1  protein FAM118A isoform X1

   UniProtKB/TrEMBL

   A0A3Q1LRB4, A0AAF6DM31

   Conserved Domains (1) summary

   pfam13289
   Location:143 → 248

   SIR2_2; SIR2-like domain

8. XM_024991459.2 → XP_024847227.1  protein FAM118A isoform X2

   UniProtKB/TrEMBL

   A0AAF6DM31

   Conserved Domains (1) summary

   pfam13289
   Location:142 → 247

   SIR2_2; SIR2-like domain