Lipo4 lipase, member O4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lipo4provided by MGI
Official Full Name: lipase, member O4provided by MGI
Primary source: MGI:MGI:3779637
See related: Ensembl:ENSMUSG00000079344 AllianceGenome:MGI:3779637
Gene type: protein coding
RefSeq status: INFERRED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm6857
Summary: Predicted to enable sterol ester esterase activity. Predicted to be involved in sterol metabolic process. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Jan 2025]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 19 C1; 19 29.17 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (33476449..33495170, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (33499049..33517770, complement)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables sterol ester esterase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in sterol metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: lipase, member O4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001323386.1 → NP_001310315.1 lipase, member O4 precursor

Status: INFERRED

Source sequence(s)

AC141640

Consensus CDS

CCDS89378.1

UniProtKB/TrEMBL

F6RR30, Q3TD80

Related

ENSMUSP00000121321.3, ENSMUST00000143522.9

Conserved Domains (2) summary

pfam00561
Location:77 → 375

Abhydrolase_1; alpha/beta hydrolase fold

pfam04083
Location:33 → 95

Abhydro_lipase; Partial alpha/beta-hydrolase lipase region