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    Tmsb15b2 thymosin beta 15b2 [ Mus musculus (house mouse) ]

    Gene ID: 100034363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmsb15b2provided by MGI
    Official Full Name
    thymosin beta 15b2provided by MGI
    Primary source
    MGI:MGI:3843061
    See related
    Ensembl:ENSMUSG00000089996 AllianceGenome:MGI:3843061
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tb15c
    Summary
    This gene is part of tandem duplication; the other copy of this gene is about 1.5 kb away. Readthrough transcripts that include two exons transcribed from each gene exist. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in CNS E18 (RPKM 11.2), CNS E14 (RPKM 8.6) and 13 other tissues See more
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    Genomic context

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    See Tmsb15b2 in Genome Data Viewer
    Location:
    X F1; X 59.1 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135855737..135858728, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136954988..136957979, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene H2B.W histone 2 Neighboring gene glycogen synthase kinase 3 alpha pseudogene Neighboring gene thymosin beta 15b like Neighboring gene thymosin beta 15b1 Neighboring gene solute carrier family 25, member 53 Neighboring gene zinc finger, CCHC domain containing 18 Neighboring gene vacuolar ATPase assembly integral membrane protein Vma21 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. Dhaese S, et al. J Mol Biol, 2009 Apr 10. PMID 19233202
    2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Readthrough Tmsb15l

    Readthrough gene: Tmsb15l, Included gene: Tmsb15b1

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin monomer binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of actin filament polymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of stress fiber assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sequestering of actin monomers IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sequestering of actin monomers IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of filamentous actin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in stress fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thymosin beta-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080967.4 → NP_001074436.1  thymosin beta-like

      Status: VALIDATED

      Source sequence(s)
      AW493156, CN842750
      Consensus CDS
      CCDS41138.1
      UniProtKB/TrEMBL
      A2AF31
      Related
      ENSMUSP00000063549.5, ENSMUST00000069803.5
      Conserved Domains (1) summary
      pfam01290
      Location:3 → 41
      Thymosin; Thymosin beta-4 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      135855737..135858728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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