Chrac1 chromatin accessibility complex 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Chrac1provided by MGI
Official Full Name: chromatin accessibility complex 1provided by MGI
Primary source: MGI:MGI:2135796
See related: Ensembl:ENSMUSG00000068391 AllianceGenome:MGI:2135796
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: YCL1; 2410152E03Rik; 2810406L04Rik
Summary: Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and protein heterodimerization activity. Predicted to be involved in DNA-templated DNA replication; nucleosome assembly; and regulation of DNA replication. Located in pericentric heterochromatin. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human CHRAC1 (chromatin accessibility complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in testis adult (RPKM 176.2), ovary adult (RPKM 25.8) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 D3; 15 33.92 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (72962261..72965924)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (73090412..73094075)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed DNA polymerase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in DNA-templated DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in nucleosome assembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of DNA replication	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of CHRAC	IBA Inferred from Biological aspect of Ancestor more info
part_of CHRAC	NAS Non-traceable Author Statement more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in pericentric heterochromatin	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: chromatin accessibility complex protein 1

Names: CHRAC-1; DNA polymerase epsilon subunit p15; NF-YC-like protein; YC-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053068.3 → NP_444298.1 chromatin accessibility complex protein 1

See identical proteins and their annotated locations for NP_444298.1

Status: PROVISIONAL

Source sequence(s)

AK010812

Consensus CDS

CCDS27516.1

UniProtKB/Swiss-Prot

Q91VG2, Q9JKP8

Related

ENSMUSP00000087197.3, ENSMUST00000089765.9

Conserved Domains (1) summary

cl23735
Location:18 → 79

H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...