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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011840.2 RefSeqGene
- Range
-
4988..35463
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001282352.2 → NP_001269281.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks several exons, uses an alternate 5'-terminal exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC130469, AF163762, AK131414, BC029308, BF510205
- Consensus CDS
-
CCDS62529.1
- UniProtKB/TrEMBL
-
Q6ZN14
- Related
- ENSP00000470501.1, ENST00000595838.5
- Conserved Domains (3) summary
-
- smart00209
Location:497 → 541
- TSP1; Thrombospondin type 1 repeats
- pfam05986
Location:193 → 305
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam08686
Location:556 → 587
- PLAC; PLAC (protease and lacunin) domain
-
NM_030957.4 → NP_112219.3 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB209515, AC130469, AF163762, AK131414, BC029308, BF510205, CN431169
- Consensus CDS
-
CCDS12206.1
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
- UniProtKB/TrEMBL
-
A0A0A0MQW6
- Related
- ENSP00000471851.1, ENST00000597188.6
- Conserved Domains (6) summary
-
- smart00209
Location:550 → 602
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:239 → 454
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01421
Location:239 → 457
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 179
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:706 → 818
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam08686
Location:1069 → 1100
- PLAC; PLAC (protease and lacunin) domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
8580240..8610715 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017027338.3 → XP_016882827.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
- UniProtKB/TrEMBL
-
A0A0A0MQW6
- Conserved Domains (6) summary
-
- smart00209
Location:550 → 602
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:239 → 454
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01421
Location:239 → 457
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 179
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:706 → 818
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam08686
Location:1069 → 1100
- PLAC; PLAC (protease and lacunin) domain
-
XM_047439480.1 → XP_047295436.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
-
XM_047439481.1 → XP_047295437.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
-
XM_047439483.1 → XP_047295439.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4
-
XM_047439482.1 → XP_047295438.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3
-
XM_047439484.1 → XP_047295440.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X5
RNA
-
XR_001753770.2 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
8567599..8598065 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054322261.1 → XP_054178236.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
-
XM_054322259.1 → XP_054178234.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
-
XM_054322260.1 → XP_054178235.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
- UniProtKB/Swiss-Prot
- M0QZE4, Q9H324
-
XM_054322263.1 → XP_054178238.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4
-
XM_054322262.1 → XP_054178237.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3
-
XM_054322264.1 → XP_054178239.1 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X5
RNA
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XR_008485207.1 RNA Sequence