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    cobL precorrin-6y-dependent methyltransferase CobL [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882678, updated on 24-Aug-2024

    Summary

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    Gene symbol
    cobL
    Gene description
    precorrin-6y-dependent methyltransferase CobL
    Locus tag
    PA2907
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3261522..3262769)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene precorrin-3 methylase CobJ Neighboring gene precorrin-2 C(20)-methyltransferase Neighboring gene precorrin-8X methylmutase Neighboring gene oxidoreductase Neighboring gene cobalt-precorrin-5B C(1)-methyltransferase Neighboring gene cobalt-precorrin-6x reductase Neighboring gene manganese efflux pump MntP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product. Blanche F, et al. J Bacteriol, 1992 Feb. PMID 1732195, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within cobalamin biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    precorrin-6y-dependent methyltransferase CobL
    NP_251597.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3261522..3262769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251597.1 precorrin-6y-dependent methyltransferase CobL [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251597.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HZU0
      Conserved Domains (2) summary
      COG2241
      Location:10 → 215
      CobL; Precorrin-6B methylase 1 [Coenzyme transport and metabolism]
      COG2242
      Location:223 → 406
      CobL; Precorrin-6B methylase 2 [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HZU0.1

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