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    popD translocator outer membrane protein PopD [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879358, updated on 24-Aug-2024

    Summary

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    Gene symbol
    popD
    Gene description
    translocator outer membrane protein PopD
    Locus tag
    PA1709
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1854849..1855736)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene type III secretion protein PcrV Neighboring gene regulatory protein PcrH Neighboring gene translocator protein PopB Neighboring gene exoenzyme S synthesis protein ExsC Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system function. Tomalka AG, et al. Mol Microbiol, 2012 Dec. PMID 23121689, Free PMC Article
    2. Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex. Romano FB, et al. J Biol Chem, 2016 Mar 18. PMID 26786106, Free PMC Article
    3. Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system. Allmond LR, et al. Infect Immun, 2003 Apr. PMID 12654846, Free PMC Article
    4. Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosis. Frithz-Lindsten E, et al. Mol Microbiol, 1998 Sep. PMID 9767584
    5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The interaction between PopB and PopD guide the assembly of a unique hetero-oligomer in membranes.
      Title: Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex.
    2. Two novel signals in PopD, one proximal to the chaperone binding site and one at the very C-terminus of the protein, are required for export of PopD before effector proteins.
      Title: A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system function.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables protein-folding chaperone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within translocation of peptides or proteins into host IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    translocator outer membrane protein PopD
    NP_250400.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1854849..1855736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250400.1 translocator outer membrane protein PopD [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250400.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5DQX2, O30530
      Conserved Domains (1) summary
      pfam05844
      Location:7 → 295
      YopD; YopD protein
    Nucleotide Protein
    Heading Accession and Version

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