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    hmg-11 HMG [ Caenorhabditis elegans ]

    Gene ID: 173805, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hmg-11
    Official Full Name
    HMG
    Primary source
    WormBase:WBGene00001976
    Locus tag
    CELE_T05A7.4
    See related
    AllianceGenome:WB:WBGene00001976
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Is expressed in several structures, including anal depressor muscle; egg-laying apparatus; excretory cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; leiomyoma; lipoma; and ovarian cancer. Orthologous to human HMGA2 (high mobility group AT-hook 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See hmg-11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (4673085..4673746)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Alpha-(1,3)-fucosyltransferase fut-5 Neighboring gene Protein kinase domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene CUB domain-containing protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SnAvi--a new tandem tag for high-affinity protein-complex purification. Schäffer U, et al. Nucleic Acids Res, 2010 Apr. PMID 20047968, Free PMC Article
    2. H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Vandamme J, et al. Nucleic Acids Res, 2015 Nov 16. PMID 26476455, Free PMC Article
    3. Maternal H3K36 and H3K27 HMTs protect germline development via regulation of the transcription factor LIN-15B. Cockrum CS, et al. Elife, 2022 Aug 3. PMID 35920536, Free PMC Article
    4. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article
    5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HMG
    NP_494825.1
    • Product from WormBase gene class hmg;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4673085..4673746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062424.10 → NP_494825.1  HMG [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494825.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEL9
      Conserved Domains (1) summary
      PRK07003
      Location:22 → 123
      PRK07003; DNA polymerase III subunits gamma and tau; Validated
    Nucleotide Protein
    Heading Accession and Version

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