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    T13H5.8 Lipid scramblase CLPTM1L [ Caenorhabditis elegans ]

    Gene ID: 174362, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T13H5.8
    Official Full Name
    Lipid scramblase CLPTM1L
    Primary source
    WormBase:WBGene00011761
    Locus tag
    CELE_T13H5.8
    See related
    AllianceGenome:WB:WBGene00011761
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in endomembrane system and membrane. Human ortholog(s) of this gene implicated in carcinoma (multiple) and lung disease (multiple). Orthologous to human CLPTM1L (CLPTM1 like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T13H5.8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (8518510..8520696)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene CRAL-TRIO domain-containing protein Neighboring gene Ribonuclease H2 subunit A Neighboring gene GH18 domain-containing protein Neighboring gene Matrin-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipid scramblase CLPTM1L
    NP_495797.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8518510..8520696
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063396.6 → NP_495797.1  Lipid scramblase CLPTM1L [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495797.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95QB1
      Conserved Domains (1) summary
      pfam05602
      Location:9 → 422
      CLPTM1; Cleft lip and palate transmembrane protein 1 (CLPTM1)
    Nucleotide Protein
    Heading Accession and Version

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