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    ZC434.4 Ribosomal RNA-processing protein 7 homolog [ Caenorhabditis elegans ]

    Gene ID: 172902, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZC434.4
    Official Full Name
    Ribosomal RNA-processing protein 7 homolog
    Primary source
    WormBase:WBGene00013892
    Locus tag
    CELE_ZC434.4
    See related
    AllianceGenome:WB:WBGene00013892
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to be part of CURI complex and UTP-C complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to several human genes including RRP7A (ribosomal RNA processing 7 homolog A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZC434.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (10331979..10333082, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF4477 domain-containing protein Neighboring gene Small ribosomal subunit protein eS7 Neighboring gene DUF3421 domain-containing protein Neighboring gene DUF3421 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of CURI complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of UTP-C complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ribosomal RNA-processing protein 7 homolog
    NP_492709.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10331979..10333082 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060308.7 → NP_492709.2  Ribosomal RNA-processing protein 7 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492709.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23314
      Conserved Domains (1) summary
      cd12951
      Location:143 → 269
      RRP7_Rrp7A; RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q23314.3

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