rpap-2 Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rpap-2
Official Full Name: Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2
Primary source: WormBase:WBGene00011143
Locus tag: CELE_R08D7.2
See related: AllianceGenome:WB:WBGene00011143
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Orthologous to human RPAP2 (RNA polymerase II associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rpap-2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 7

Sequence:: Chromosome: III; NC_003281.10 (8967967..8969658)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R08D7.2 (e-PCR)
- UniSTS:321626

R08D7.1 (e-PCR)
- UniSTS:307856

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA polymerase II CTD heptapeptide repeat phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II CTD heptapeptide repeat phosphatase activity	IEA Inferred from Electronic Annotation more info
enables RNA polymerase core enzyme binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2

NP_498983.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8967967..8969658

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066582.8 → NP_498983.1 Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498983.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P30641

Conserved Domains (1) summary

pfam04181
Location:46 → 113

RPAP2_Rtr1; Rtr1/RPAP2 family