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    hpo-28 Major sperm protein [ Caenorhabditis elegans ]

    Gene ID: 175798, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hpo-28
    Official Full Name
    Major sperm protein
    Primary source
    WormBase:WBGene00015148
    Locus tag
    CELE_B0336.11
    See related
    AllianceGenome:WB:WBGene00015148
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in cytoskeleton and membrane. Predicted to be active in endomembrane system and endoplasmic reticulum-endosome membrane contact site. Orthologous to human MOSPD2 (motile sperm domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See hpo-28 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (5706717..5709324, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RGS domain-containing protein;Regulator of G-protein signaling rgs-5 Neighboring gene Protein SWAP;SURP motif domain-containing protein;Suppressor of white apricot N-terminal domain-containing protein Neighboring gene Large ribosomal subunit protein uL14 Neighboring gene Uncharacterized protein Neighboring gene C3H1-type domain-containing protein;RRM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
    2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum-endosome membrane contact site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Major sperm protein
    NP_001379556.1
    • Confirmed by transcript evidence
    NP_498232.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5706717..5709324 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065831.6 → NP_498232.3  Major sperm protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498232.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q10956
      Conserved Domains (2) summary
      cd00170
      Location:105 → 247
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
      pfam00635
      Location:381 → 460
      Motile_Sperm; MSP (Major sperm protein) domain

    2. NM_001392109.1 → NP_001379556.1  Major sperm protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KY79
      Conserved Domains (1) summary
      pfam00635
      Location:103 → 207
      Motile_Sperm; MSP (Major sperm protein) domain
    Nucleotide Protein
    Heading Accession and Version

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