amdh-1 putative imidazolonepropionase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: amdh-1
Official Full Name: putative imidazolonepropionase
Primary source: WormBase:WBGene00020436
Locus tag: CELE_T12A2.1
See related: AllianceGenome:WB:WBGene00020436
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable imidazolonepropionase activity. Predicted to be involved in L-histidine catabolic process. Predicted to be located in cytoplasm. Orthologous to human AMDHD1 (amidohydrolase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See amdh-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 9

Sequence:: Chromosome: III; NC_003281.10 (6251811..6271283)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

T12A2.13 (e-PCR)
- UniSTS:310811

T12A2.9 (e-PCR)
- UniSTS:310818

T12A2.1 (e-PCR)
- UniSTS:314970

T12A2.12 (e-PCR)
- UniSTS:314971

T12A2.10 (e-PCR)
- UniSTS:306277

T12A2.11 (e-PCR)
- UniSTS:306278

C18F10.4 (e-PCR)
- UniSTS:308605

C18F10.6 (e-PCR)
- UniSTS:308606

C18F10.8 (e-PCR)
- UniSTS:306127

C18F10.5 (e-PCR)
- UniSTS:317677

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IEA Inferred from Electronic Annotation more info
enables imidazolonepropionase activity	IBA Inferred from Biological aspect of Ancestor more info
enables imidazolonepropionase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-histidine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-histidine catabolic process to glutamate and formamide	IEA Inferred from Electronic Annotation more info
involved_in L-histidine catabolic process to glutamate and formate	IEA Inferred from Electronic Annotation more info
involved_in L-histidine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative imidazolonepropionase

NP_498363.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6251811..6271283

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065962.4 → NP_498363.2 putative imidazolonepropionase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498363.2

Status: REVIEWED

UniProtKB/TrEMBL

Q22419

Conserved Domains (1) summary

TIGR01224
Location:39 → 429

hutI; imidazolonepropionase