kcmf-1 Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: kcmf-1
Official Full Name: Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein
Primary source: WormBase:WBGene00022785
Locus tag: CELE_ZK652.6
See related: AllianceGenome:WB:WBGene00022785
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to be located in nucleus and synapse. Predicted to be active in plasma membrane. Orthologous to human KCMF1 (potassium channel modulatory factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See kcmf-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 9

Sequence:: Chromosome: III; NC_003281.10 (7829411..7832494)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK652.6 (e-PCR)
- UniSTS:310532

STS3-166 (e-PCR)
- UniSTS:242008

C27D11.1 (e-PCR)
- UniSTS:308651

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of cell communication	IEA Inferred from Electronic Annotation more info
involved_in regulation of signaling	IEA Inferred from Electronic Annotation more info
involved_in synaptic signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein

NP_001023028.2

Confirmed by transcript evidence

NP_001299933.1

Confirmed by transcript evidence

NP_001299934.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7829411..7832494

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001027857.6 → NP_001023028.2 zf-Di19 domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

P34664, Q7Z143

Conserved Domains (2) summary

cd02338
Location:12 → 68

ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...

pfam05605
Location:93 → 130

zf-Di19; Drought induced 19 protein (Di19), zinc-binding
NM_001313004.3 → NP_001299933.1 Drought induced 19 protein type zinc-binding domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

P34664, Q7Z143

UniProtKB/TrEMBL

A0A0K3AS04

Conserved Domains (1) summary

pfam05605
Location:29 → 66

zf-Di19; Drought induced 19 protein (Di19), zinc-binding
NM_001313005.3 → NP_001299934.1 zf-Di19 domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AUB7