ZK686.3 putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ZK686.3
Official Full Name: putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Primary source: WormBase:WBGene00022793
Locus tag: CELE_ZK686.3
See related: AllianceGenome:WB:WBGene00022793
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Orthologous to human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ZK686.3 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (7767573..7769063, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK686.3 (e-PCR)
- UniSTS:310538

ZK686.4 (e-PCR)
- UniSTS:322473

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in protein N-linked glycosylation via asparagine	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of oligosaccharyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

NP_498691.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7767573..7769063 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066290.7 → NP_498691.1 putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498691.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P34669

Conserved Domains (1) summary

pfam04756
Location:147 → 313

OST3_OST6; OST3 / OST6 family