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    INPPL1 inositol polyphosphate phosphatase like 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718421, updated on 17-Aug-2024

    Summary

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    Official Symbol
    INPPL1provided by VGNC
    Official Full Name
    inositol polyphosphate phosphatase like 1provided by VGNC
    Primary source
    VGNC:VGNC:73752
    See related
    Ensembl:ENSMMUG00000010451
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See INPPL1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (65196068..65210420)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (64164807..64179151)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene folate receptor beta Neighboring gene paired like homeobox 2A Neighboring gene docking protein 1 pseudogene Neighboring gene splicing factor U2AF 35 kDa subunit-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
    Names
    phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
    NP_001247768.1
    XP_014970616.2
    XP_014970617.2
    XP_028688685.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260839.1 → NP_001247768.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

      See identical proteins and their annotated locations for NP_001247768.1

      Status: PROVISIONAL

      Source sequence(s)
      JU475481
      UniProtKB/TrEMBL
      A0A1D5Q071, H9F5V6, H9Z8L9
      Related
      ENSMMUP00000041433.2, ENSMMUT00000062600.2
      Conserved Domains (4) summary
      cd09491
      Location:1194 → 1256
      SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
      cd09101
      Location:424 → 727
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      smart00454
      Location:1202 → 1258
      SAM; Sterile alpha motif
      cd10343
      Location:17 → 119
      SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      65196068..65210420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115130.2 → XP_014970616.2  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

      UniProtKB/TrEMBL
      F7CRA7, H9F5V6
      Related
      ENSMMUP00000013695.4, ENSMMUT00000014619.4
      Conserved Domains (4) summary
      cd09491
      Location:1251 → 1313
      SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
      cd09101
      Location:481 → 784
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      pfam15685
      Location:959 → 1103
      GGN; Gametogenetin
      cl15255
      Location:17 → 176
      SH2; Src homology 2 (SH2) domain

    2. XM_015115131.2 → XP_014970617.2  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3

      UniProtKB/TrEMBL
      H9F5V6
      Conserved Domains (3) summary
      cd09101
      Location:481 → 784
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      pfam15685
      Location:959 → 1103
      GGN; Gametogenetin
      cl15255
      Location:17 → 176
      SH2; Src homology 2 (SH2) domain

    3. XM_028832852.1 → XP_028688685.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2

      UniProtKB/TrEMBL
      G7NE91
      Conserved Domains (4) summary
      cd09491
      Location:1184 → 1246
      SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
      cd09101
      Location:414 → 717
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      pfam15685
      Location:892 → 1036
      GGN; Gametogenetin
      cl15255
      Location:52 → 109
      SH2; Src homology 2 (SH2) domain
    Nucleotide Protein
    Heading Accession and Version

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