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    ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720191, updated on 5-Mar-2024

    Summary

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    Gene symbol
    ATP1A2
    Gene description
    ATPase Na+/K+ transporting subunit alpha 2
    See related
    Ensembl:ENSMMUG00000017833
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See ATP1A2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (90793154..90821026, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (134851104..134877377)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114670176 Neighboring gene calsequestrin 1 Neighboring gene ATPase Na+/K+ transporting subunit alpha 4 Neighboring gene immunoglobulin superfamily member 8 Neighboring gene potassium inwardly rectifying channel subfamily J member 9 Neighboring gene potassium inwardly rectifying channel subfamily J member 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables P-type sodium:potassium-exchanging transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular sodium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium/potassium-transporting ATPase subunit alpha-2
    Names
    ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide
    sodium/potassium-transporting ATPase subunit alpha-2 proprotein
    NP_001252615.1
    XP_028702220.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265686.1 → NP_001252615.1  sodium/potassium-transporting ATPase subunit alpha-2

      See identical proteins and their annotated locations for NP_001252615.1

      Status: PROVISIONAL

      Source sequence(s)
      JV636174
      UniProtKB/TrEMBL
      A0A1D5R1L9, F6WKK2, H9FUW0
      Related
      ENSMMUP00000054203.1, ENSMMUT00000076532.2
      Conserved Domains (6) summary
      smart00831
      Location:38 → 112
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      COG4087
      Location:603 → 749
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01106
      Location:30 → 1020
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
      pfam00122
      Location:132 → 363
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:796 → 1005
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam13246
      Location:425 → 518
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      90793154..90821026 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846387.1 → XP_028702220.1  sodium/potassium-transporting ATPase subunit alpha-2 isoform X1

      UniProtKB/TrEMBL
      F6WKK2, F7DR13, H9FUW0
      Related
      ENSMMUP00000023447.4, ENSMMUT00000025062.4
      Conserved Domains (1) summary
      TIGR01106
      Location:30 → 952
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    Nucleotide Protein
    Heading Accession and Version

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