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    PKN2 protein kinase N2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693505, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PKN2provided by VGNC
    Official Full Name
    protein kinase N2provided by VGNC
    Primary source
    VGNC:VGNC:76015
    See related
    Ensembl:ENSMMUG00000020588
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PKN2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (135623964..135787033, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (88889903..89052449)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999568 Neighboring gene general transcription factor IIB Neighboring gene U6 spliceosomal RNA Neighboring gene transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) pseudogene Neighboring gene COP9 signalosome complex subunit 6 pseudogene Neighboring gene uncharacterized LOC106999565

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase N2
    Names
    serine/threonine-protein kinase N2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      135623964..135787033 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028831697.1 → XP_028687530.1  serine/threonine-protein kinase N2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QYM8
      Conserved Domains (5) summary
      cd08687
      Location:329 → 410
      C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
      cd11622
      Location:42 → 107
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11635
      Location:209 → 282
      HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
      cd05589
      Location:594 → 919
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:127 → 201
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    2. XM_015144453.2 → XP_014999939.1  serine/threonine-protein kinase N2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QYM8, F7C0E0
      Related
      ENSMMUP00000027100.4, ENSMMUT00000028962.4
      Conserved Domains (5) summary
      cd11622
      Location:42 → 107
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11635
      Location:209 → 282
      HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
      cd05589
      Location:608 → 933
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:127 → 201
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl14603
      Location:389 → 471
      C2; C2 domain

    3. XM_015144447.2 → XP_014999933.1  serine/threonine-protein kinase N2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QYM8, H9FX45
      Related
      ENSMMUP00000053159.2, ENSMMUT00000063363.2
      Conserved Domains (5) summary
      cd08687
      Location:389 → 472
      C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
      cd11622
      Location:42 → 107
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11635
      Location:209 → 282
      HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
      cd05589
      Location:656 → 981
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:127 → 201
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    Nucleotide Protein
    Heading Accession and Version

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