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    ITPA inosine triphosphatase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717257, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITPAprovided by VGNC
    Official Full Name
    inosine triphosphataseprovided by VGNC
    Primary source
    VGNC:VGNC:73801
    Locus tag
    EGK_02612
    See related
    Ensembl:ENSMMUG00000061481
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITPA in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (63275324..63295483, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (36049460..36066141)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 9 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene NEDD8-conjugating enzyme UBE2F-like Neighboring gene solute carrier family 4 member 11 Neighboring gene DDRGK domain containing 1 Neighboring gene leucine zipper tumor suppressor family member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleoside triphosphate diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleoside triphosphate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inosine triphosphate pyrophosphatase
    Names
    Inosine triphosphate pyrophosphatase
    inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
    XP_001115179.1
    XP_028684094.1
    XP_028684095.1
    XP_028684096.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      63275324..63295483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828263.1 → XP_028684096.1  inosine triphosphate pyrophosphatase isoform X4

      Conserved Domains (1) summary
      cd00515
      Location:10 → 136
      HAM1; NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A ...

    2. XM_028828261.1 → XP_028684094.1  inosine triphosphate pyrophosphatase isoform X1

      Conserved Domains (1) summary
      cd00515
      Location:60 → 225
      HAM1; NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A ...

    3. XM_028828262.1 → XP_028684095.1  inosine triphosphate pyrophosphatase isoform X3

      Conserved Domains (1) summary
      cd00515
      Location:10 → 147
      HAM1; NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A ...

    4. XM_001115179.4 → XP_001115179.1  inosine triphosphate pyrophosphatase isoform X2

      See identical proteins and their annotated locations for XP_001115179.1

      UniProtKB/TrEMBL
      A0A8J8XPQ7, F6QR76, G7N2U3
      Related
      ENSMMUP00000071577.1, ENSMMUT00000101399.1
      Conserved Domains (1) summary
      cd00515
      Location:10 → 188
      HAM1; NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A ...
    Nucleotide Protein
    Heading Accession and Version

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