U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706150, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    EDEM2provided by VGNC
    Official Full Name
    ER degradation enhancing alpha-mannosidase like protein 2provided by VGNC
    Primary source
    VGNC:VGNC:72050
    Locus tag
    EGK_02472
    See related
    Ensembl:ENSMMUG00000010032
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See EDEM2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (70319902..70353084, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (28985811..29018919)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 7B Neighboring gene microRNA mir-499 Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene small nucleolar RNA SNORD56 Neighboring gene uncharacterized LOC107000422 Neighboring gene protein C receptor Neighboring gene matrix metallopeptidase 24 Neighboring gene MMP24 opposite strand

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endoplasmic reticulum mannose trimming IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ER degradation-enhancing alpha-mannosidase-like protein 2
    Names
    ER degradation-enhancing alpha-mannosidase-like 2
    NP_001247965.1
    XP_028683128.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261036.1 → NP_001247965.1  ER degradation-enhancing alpha-mannosidase-like protein 2 precursor

      See identical proteins and their annotated locations for NP_001247965.1

      Status: PROVISIONAL

      Source sequence(s)
      JU472490
      UniProtKB/TrEMBL
      A0A8J8Y7A5, F6Q1A3, G7N500, H9ER27
      Related
      ENSMMUP00000013112.4, ENSMMUT00000014003.4
      Conserved Domains (1) summary
      pfam01532
      Location:42 → 480
      Glyco_hydro_47; Glycosyl hydrolase family 47

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      70319902..70353084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827295.1 → XP_028683128.1  ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1

      UniProtKB/TrEMBL
      F7AUH8
      Related
      ENSMMUP00000037782.3, ENSMMUT00000044763.3
      Conserved Domains (1) summary
      pfam01532
      Location:36 → 443
      Glyco_hydro_47; Glycosyl hydrolase family 47
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.