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    SREBF2 sterol regulatory element binding transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712307, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SREBF2provided by VGNC
    Official Full Name
    sterol regulatory element binding transcription factor 2provided by VGNC
    Primary source
    VGNC:VGNC:77881
    See related
    Ensembl:ENSMMUG00000003357
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SREBF2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (9599436..9679964, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (83916568..83997145)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 13C Neighboring gene shisa family member 8 Neighboring gene coiled-coil domain containing 134 Neighboring gene uncharacterized LOC107000676 Neighboring gene meiotic double-stranded break formation protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cholesterol storage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol regulatory element-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      9599436..9679964 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150475.2 → XP_015005961.2  sterol regulatory element-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      F7ECM3
      Related
      ENSMMUP00000004471.4, ENSMMUT00000004743.4
      Conserved Domains (1) summary
      pfam00010
      Location:438 → 488
      HLH; Helix-loop-helix DNA-binding domain

    2. XM_028827651.1 → XP_028683484.1  sterol regulatory element-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      F7ECN3
      Conserved Domains (1) summary
      pfam00010
      Location:305 → 355
      HLH; Helix-loop-helix DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version

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