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    GSTA3 glutathione S-transferase alpha 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709498, updated on 9-Nov-2023

    Summary

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    Gene symbol
    GSTA3
    Gene description
    glutathione S-transferase alpha 3
    See related
    Ensembl:ENSMMUG00000017137
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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    Genomic context

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    See GSTA3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (116691549..116772664)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (53825876..53836164, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase alpha 4 Neighboring gene uncharacterized LOC114677587 Neighboring gene uncharacterized LOC114677588 Neighboring gene uncharacterized LOC100424751 Neighboring gene glutathione S-transferase A5 Neighboring gene glutathione S-transferase alpha 1 Neighboring gene glutathione S-transferase A1-like Neighboring gene glutathione S-transferase alpha 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic identification and characterization of glutathione S-transferases in cynomolgus macaque. Uno Y, et al. Biochem Pharmacol, 2013 Sep 1. PMID 23827461
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in xenobiotic metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular exosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase A3
    NP_001248197.1
    XP_028702609.1
    XP_028702610.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261268.1 → NP_001248197.1  glutathione S-transferase A3

      See identical proteins and their annotated locations for NP_001248197.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046857
      UniProtKB/TrEMBL
      A0A5F7ZPN2, I2CV62
      Conserved Domains (2) summary
      cd03208
      Location:86 → 220
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cd03077
      Location:4 → 82
      GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      116691549..116772664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846776.1 → XP_028702609.1  glutathione S-transferase A3 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZPN2, I2CV62
      Related
      ENSMMUP00000067577.1, ENSMMUT00000103771.1
      Conserved Domains (2) summary
      cd03208
      Location:86 → 220
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cd03077
      Location:4 → 82
      GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    2. XM_028846777.1 → XP_028702610.1  glutathione S-transferase A3 isoform X2

      Conserved Domains (2) summary
      cd03208
      Location:36 → 170
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cl00388
      Location:1 → 32
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    Nucleotide Protein
    Heading Accession and Version

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