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    FBXL12 F-box and leucine rich repeat protein 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710855, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FBXL12provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 12provided by VGNC
    Primary source
    VGNC:VGNC:72502
    Locus tag
    EGK_10073
    See related
    Ensembl:ENSMMUG00000007875
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FBXL12 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (9554842..9563475, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (9810129..9818963, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S4 pseudogene Neighboring gene zinc finger protein 562 Neighboring gene zinc finger protein 846 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 pseudogene Neighboring gene ubiquitin like 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      9554842..9563475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122823.2 → XP_014978309.1  F-box/LRR-repeat protein 12 isoform X2

      UniProtKB/TrEMBL
      H9FBD0
      Conserved Domains (3) summary
      cd09293
      Location:68 → 173
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:51 → 72
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd21340
      Location:114 → 238
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    2. XM_015122824.2 → XP_014978310.1  F-box/LRR-repeat protein 12 isoform X2

      UniProtKB/TrEMBL
      H9FBD0
      Conserved Domains (3) summary
      cd09293
      Location:68 → 173
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:51 → 72
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd21340
      Location:114 → 238
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    3. XM_015122821.2 → XP_014978307.1  F-box/LRR-repeat protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A663D825, A0A8J8XF27, F7B6H8, G7NKX8, H9FBD0
      Related
      ENSMMUP00000010344.4, ENSMMUT00000011032.4
      Conserved Domains (4) summary
      cd09293
      Location:121 → 226
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    4. XM_015122822.2 → XP_014978308.1  F-box/LRR-repeat protein 12 isoform X2

      UniProtKB/TrEMBL
      H9FBD0
      Conserved Domains (3) summary
      cd09293
      Location:68 → 173
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:51 → 72
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd21340
      Location:114 → 238
      PPP1R42; protein phosphatase 1 regulatory subunit 42
    Nucleotide Protein
    Heading Accession and Version

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