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    CBFB core-binding factor subunit beta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695767, updated on 5-Mar-2024

    Summary

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    Gene symbol
    CBFB
    Gene description
    core-binding factor subunit beta
    See related
    Ensembl:ENSMMUG00000058815
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CBFB in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (54207708..54284953)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (51299123..51376352)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene cocaine esterase Neighboring gene carboxylesterase 4A Neighboring gene phagosome assembly factor 1 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Neighboring gene TNFRSF1A associated via death domain Neighboring gene F-box and leucine rich repeat protein 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors. Hultquist JF, et al. J Virol, 2012 Mar. PMID 22205746, Free PMC Article
    2. Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Jäger S, et al. Nature, 2011 Dec 21. PMID 22190037, Free PMC Article
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Vif proteins of human and simian immunodeficiency viruses require cellular CBFbeta to degrade APOBEC3G.
      Title: Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors.
    2. simian immunodeficiency virus (SIV) Vif binds to and requires CBF-beta to degrade rhesus macaque APOBEC3G
      Title: Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of core-binding factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    core-binding factor subunit beta
    Names
    core-binding factor beta subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266558.1 → NP_001253487.1  core-binding factor subunit beta

      See identical proteins and their annotated locations for NP_001253487.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043621
      UniProtKB/TrEMBL
      F7EFS7
      Related
      ENSMMUP00000070667.1, ENSMMUT00000098957.1
      Conserved Domains (1) summary
      pfam02312
      Location:1 → 167
      CBF_beta; Core binding factor beta subunit

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      54207708..54284953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126323.2 → XP_014981809.1  core-binding factor subunit beta isoform X1

      UniProtKB/TrEMBL
      H9G176
      Conserved Domains (1) summary
      pfam02312
      Location:1 → 167
      CBF_beta; Core binding factor beta subunit

    2. XM_028840380.1 → XP_028696213.1  core-binding factor subunit beta isoform X3

      Conserved Domains (1) summary
      pfam02312
      Location:1 → 128
      CBF_beta; Core binding factor beta subunit

    3. XM_028840379.1 → XP_028696212.1  core-binding factor subunit beta isoform X2

      Conserved Domains (1) summary
      pfam02312
      Location:1 → 128
      CBF_beta; Core binding factor beta subunit
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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