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    BRF1 BRF1 RNA polymerase III transcription initiation factor subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709533, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BRF1provided by VGNC
    Official Full Name
    BRF1 RNA polymerase III transcription initiation factor subunitprovided by VGNC
    Primary source
    VGNC:VGNC:84314
    See related
    Ensembl:ENSMMUG00000029174
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See BRF1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (167520615..167622398, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (167575518..167655325, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene jagged canonical Notch ligand 2 Neighboring gene nudix hydrolase 14 Neighboring gene BTB domain containing 6 Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC106999596 Neighboring gene testis expressed 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase III general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase III type 3 promoter sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables TBP-class protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription factor TFIIIB complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor IIIB 90 kDa subunit
    Names
    BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
    zinc finger protein 36, C3H type-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      167520615..167622398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028851951.1 → XP_028707784.1  transcription factor IIIB 90 kDa subunit isoform X5

      UniProtKB/TrEMBL
      I0FR63
      Conserved Domains (2) summary
      COG1405
      Location:1 → 151
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      pfam07741
      Location:335 → 431
      BRF1; Brf1-like TBP-binding domain

    2. XM_028851950.1 → XP_028707783.1  transcription factor IIIB 90 kDa subunit isoform X4

      UniProtKB/TrEMBL
      I0FR63
      Conserved Domains (2) summary
      COG1405
      Location:1 → 151
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      pfam07741
      Location:335 → 453
      BRF1; Brf1-like TBP-binding domain

    3. XM_015144614.2 → XP_015000100.1  transcription factor IIIB 90 kDa subunit isoform X2

      UniProtKB/TrEMBL
      F6RDQ4, H9FTI7, I0FR63
      Related
      ENSMMUP00000032516.3, ENSMMUT00000039431.3
      Conserved Domains (2) summary
      COG1405
      Location:4 → 266
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      pfam07741
      Location:450 → 546
      BRF1; Brf1-like TBP-binding domain

    4. XM_028851948.1 → XP_028707781.1  transcription factor IIIB 90 kDa subunit isoform X1

      UniProtKB/TrEMBL
      I0FR63
      Conserved Domains (2) summary
      COG1405
      Location:4 → 278
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      pfam07741
      Location:462 → 558
      BRF1; Brf1-like TBP-binding domain

    5. XM_028851949.1 → XP_028707782.1  transcription factor IIIB 90 kDa subunit isoform X3

      UniProtKB/TrEMBL
      I0FR63
      Conserved Domains (2) summary
      COG1405
      Location:4 → 239
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      pfam07741
      Location:423 → 519
      BRF1; Brf1-like TBP-binding domain

    6. XM_028851952.1 → XP_028707785.1  transcription factor IIIB 90 kDa subunit isoform X7

      Conserved Domains (1) summary
      pfam07741
      Location:212 → 308
      BRF1; Brf1-like TBP-binding domain

    7. XM_015144618.2 → XP_015000104.1  transcription factor IIIB 90 kDa subunit isoform X6

      Conserved Domains (2) summary
      pfam07741
      Location:246 → 342
      BRF1; Brf1-like TBP-binding domain
      cd20554
      Location:1 → 66
      CYCLIN_TFIIIB90_rpt2; second cyclin box found in transcription factor IIIB 90 kDa subunit (TFIIIB90) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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