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    ADCYAP1R1 ADCYAP receptor type I [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695483, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADCYAP1R1provided by VGNC
    Official Full Name
    ADCYAP receptor type Iprovided by VGNC
    Primary source
    VGNC:VGNC:69526
    See related
    Ensembl:ENSMMUG00000005299
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADCYAP1R1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (84010535..84070078, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (77041336..77100941, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997465 Neighboring gene uncharacterized LOC114676946 Neighboring gene small integral membrane protein 14 pseudogene Neighboring gene uncharacterized LOC114676947 Neighboring gene growth hormone releasing hormone receptor Neighboring gene aquaporin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pituitary adenylate cyclase-activating peptide induces neurite outgrowth in cultured monkey trigeminal ganglion cells: involvement of receptor PAC1. Nakajima E, et al. Mol Vis, 2013. PMID 23378731, Free PMC Article
    2. PACAP receptor (PAC1-R) expression in rat and rhesus monkey thymus. Tokuda N, et al. Ann N Y Acad Sci, 2006 Jul. PMID 16888229
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. cultured trigeminal gangion cells contained neuronal ganglion and Schwann cells, and the PAC1 receptor for PACAP was expressed in both cell types
      Title: Pituitary adenylate cyclase-activating peptide induces neurite outgrowth in cultured monkey trigeminal ganglion cells: involvement of receptor PAC1.
    2. PAC1-R-positive cells were also seen in the thymic medulla of the rhesus monkey
      Title: PACAP receptor (PAC1-R) expression in rat and rhesus monkey thymus.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables vasoactive intestinal polypeptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pituitary adenylate cyclase-activating polypeptide type I receptor
    Names
    adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      84010535..84070078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015133766.2 → XP_014989252.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X8

      UniProtKB/TrEMBL
      A0A1D5QCN0, G7MLJ5
      Related
      ENSMMUP00000045799.2, ENSMMUT00000073710.2
      Conserved Domains (2) summary
      pfam00002
      Location:129 → 375
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 116
      HRM; Hormone receptor domain

    2. XM_015133764.2 → XP_014989250.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X6

      UniProtKB/TrEMBL
      G7MLJ5
      Related
      ENSMMUP00000007005.4, ENSMMUT00000007455.4
      Conserved Domains (2) summary
      pfam00002
      Location:129 → 403
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 116
      HRM; Hormone receptor domain

    3. XM_028845893.1 → XP_028701726.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X5

      UniProtKB/TrEMBL
      G7MLJ5
      Conserved Domains (3) summary
      pfam02793
      Location:52 → 123
      HRM; Hormone receptor domain
      cd14964
      Location:139 → 163
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:136 → 430
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. XM_015133762.2 → XP_014989248.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X4

      UniProtKB/TrEMBL
      G7MLJ5
      Related
      ENSMMUP00000007003.4, ENSMMUT00000007453.4
      Conserved Domains (2) summary
      pfam00002
      Location:136 → 410
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 123
      HRM; Hormone receptor domain

    5. XM_015133765.2 → XP_014989251.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X7

      UniProtKB/TrEMBL
      G7MLJ5
      Related
      ENSMMUP00000059318.2, ENSMMUT00000063188.2
      Conserved Domains (2) summary
      pfam00002
      Location:150 → 396
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 137
      HRM; Hormone receptor domain

    6. XM_015133761.2 → XP_014989247.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X3

      UniProtKB/TrEMBL
      G7MLJ5
      Conserved Domains (2) summary
      pfam00002
      Location:150 → 423
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 137
      HRM; Hormone receptor domain

    7. XM_015133760.2 → XP_014989246.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1

      UniProtKB/TrEMBL
      A0A1D5QU32, G7MLJ5
      Related
      ENSMMUP00000051562.1, ENSMMUT00000055695.2
      Conserved Domains (2) summary
      pfam00002
      Location:150 → 424
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:52 → 137
      HRM; Hormone receptor domain

    8. XM_028845892.1 → XP_028701725.1  pituitary adenylate cyclase-activating polypeptide type I receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5RC98, G7MLJ5
      Related
      ENSMMUP00000057940.2, ENSMMUT00000054735.2
      Conserved Domains (2) summary
      cd15987
      Location:150 → 445
      7tmB1_PACAP-R1; pituitary adenylate cyclase-activating polypeptide type 1 receptor, member of the class B family of seven-transmembrane G protein-coupled receptors
      pfam02793
      Location:52 → 137
      HRM; Hormone receptor domain
    Nucleotide Protein
    Heading Accession and Version

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