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    CA12 carbonic anhydrase 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705838, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CA12provided by VGNC
    Official Full Name
    carbonic anhydrase 12provided by VGNC
    Primary source
    VGNC:VGNC:70488
    Locus tag
    EGK_17571
    See related
    Ensembl:ENSMMUG00000021338
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CA12 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (39765275..39825655, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (39905105..39965238, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene RAB8B, member RAS oncogene family Neighboring gene uncharacterized LOC114679424 Neighboring gene aph-1 homolog B, gamma-secretase subunit Neighboring gene ubiquitin specific peptidase 3 Neighboring gene F-box and leucine-rich protein 22-like Neighboring gene F-box and leucine rich repeat protein 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbonic anhydrase 12
    NP_001244753.1
    XP_014997838.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257824.1 → NP_001244753.1  carbonic anhydrase 12 precursor

      See identical proteins and their annotated locations for NP_001244753.1

      Status: PROVISIONAL

      Source sequence(s)
      JU336298
      UniProtKB/TrEMBL
      A0A1D5QX25, A0A5F8A7Y0, H9FZJ2
      Related
      ENSMMUP00000052605.2, ENSMMUT00000071555.2
      Conserved Domains (1) summary
      cd03126
      Location:39 → 289
      alpha_CA_XII_XIV; Carbonic anhydrase alpha, isozymes XII and XIV. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      39765275..39825655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015142352.2 → XP_014997838.1  carbonic anhydrase 12 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZSY4, A0A5F8A7Y0, A0A8J8XEQ8, F7DLJ4
      Related
      ENSMMUP00000067749.1, ENSMMUT00000103829.1
      Conserved Domains (1) summary
      cd03126
      Location:39 → 289
      alpha_CA_XII_XIV; Carbonic anhydrase alpha, isozymes XII and XIV. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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