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    SIAH1 siah E3 ubiquitin protein ligase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716629, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SIAH1provided by VGNC
    Official Full Name
    siah E3 ubiquitin protein ligase 1provided by VGNC
    Primary source
    VGNC:VGNC:77214
    Locus tag
    EGK_12755
    See related
    Ensembl:ENSMMUG00000007400
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SIAH1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (35419607..35510756, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (32133329..32224246, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily C member 11 Neighboring gene lon peptidase 2, peroxisomal Neighboring gene ubiquitin-like Neighboring gene small nucleolar RNA U13 Neighboring gene molybdenum cofactor biosynthesis protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase SIAH1
    Names
    seven in absentia homolog 1
    NP_001247767.1
    XP_014981545.1
    XP_014981546.1
    XP_014981547.1
    XP_014981551.1
    XP_028696422.1
    XP_028696423.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260838.2 → NP_001247767.1  E3 ubiquitin-protein ligase SIAH1

      See identical proteins and their annotated locations for NP_001247767.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043508
      UniProtKB/TrEMBL
      A0A8J8YH02, F6WEY4, G7NP94
      Related
      ENSMMUP00000014922.3, ENSMMUT00000015923.4
      Conserved Domains (2) summary
      cd16751
      Location:70 → 109
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:113 → 309
      Sina; Seven in absentia protein family

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      35419607..35510756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126061.2 → XP_014981547.1  E3 ubiquitin-protein ligase SIAH1 isoform X3

      UniProtKB/TrEMBL
      F6T3K3
      Conserved Domains (2) summary
      cd16751
      Location:39 → 78
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:82 → 278
      Sina; Seven in absentia protein family

    2. XM_015126060.2 → XP_014981546.1  E3 ubiquitin-protein ligase SIAH1 isoform X3

      UniProtKB/TrEMBL
      F6T3K3
      Related
      ENSMMUP00000070577.1, ENSMMUT00000105660.1
      Conserved Domains (2) summary
      cd16751
      Location:39 → 78
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:82 → 278
      Sina; Seven in absentia protein family

    3. XM_015126059.2 → XP_014981545.1  E3 ubiquitin-protein ligase SIAH1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZGZ6
      Related
      ENSMMUP00000063898.1, ENSMMUT00000079611.1
      Conserved Domains (1) summary
      pfam03145
      Location:84 → 280
      Sina; Seven in absentia protein family

    4. XM_028840589.1 → XP_028696422.1  E3 ubiquitin-protein ligase SIAH1 isoform X1

      Conserved Domains (2) summary
      cd16751
      Location:68 → 107
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:111 → 307
      Sina; Seven in absentia protein family

    5. XM_015126065.1 → XP_014981551.1  E3 ubiquitin-protein ligase SIAH1 isoform X3

      UniProtKB/TrEMBL
      F6T3K3
      Related
      ENSMMUP00000009709.3, ENSMMUT00000010347.4
      Conserved Domains (2) summary
      cd16751
      Location:39 → 78
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:82 → 278
      Sina; Seven in absentia protein family

    6. XM_028840590.1 → XP_028696423.1  E3 ubiquitin-protein ligase SIAH1 isoform X3

      UniProtKB/TrEMBL
      F6T3K3
      Conserved Domains (2) summary
      cd16751
      Location:39 → 78
      RING-HC_SIAH1; RING finger, HC subclass, found in seven in absentia homolog 1 (SIAH1) and similar proteins
      pfam03145
      Location:82 → 278
      Sina; Seven in absentia protein family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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