SP100 SP100 nuclear antigen [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: SP100
Gene description: SP100 nuclear antigen
See related: Ensembl:ENSMMUG00000016575
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: SP100-HMG
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	12	NC_041765.1 (117847420..117978266)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	12	NC_027904.1 (112860752..112992022)

Chromosome 12 - NC_041765.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

D2S2641 (e-PCR)
- UniSTS:11877

PMC56901P2 (e-PCR)
- UniSTS:273358

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: nuclear autoantigen Sp-100

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041765.1 Reference Mmul_10 Primary Assembly

Range

117847420..117978266

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015111312.2 → XP_014966798.1 nuclear autoantigen Sp-100 isoform X9

UniProtKB/TrEMBL

A0A1D5R4K1

Conserved Domains (5) summary

cd05501
Location:751 → 852

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:682 → 723

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:578 → 653

SAND; SAND domain

pfam03172
Location:16 → 110

Sp100; Sp100 domain

cl00748
Location:513 → 582

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111304.2 → XP_014966790.1 nuclear autoantigen Sp-100 isoform X2

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (5) summary

cd05501
Location:784 → 885

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:715 → 756

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:611 → 686

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain

cl00748
Location:546 → 615

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111303.2 → XP_014966789.1 nuclear autoantigen Sp-100 isoform X1

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (5) summary

cd05501
Location:787 → 888

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:718 → 759

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:614 → 689

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain

cl00748
Location:549 → 618

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111306.2 → XP_014966792.1 nuclear autoantigen Sp-100 isoform X4

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (4) summary

cd05501
Location:772 → 873

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:703 → 744

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:599 → 674

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain
XM_015111305.2 → XP_014966791.2 nuclear autoantigen Sp-100 isoform X3

UniProtKB/TrEMBL

A0A1D5Q7N7

Related

ENSMMUP00000044053.2, ENSMMUT00000065410.2

Conserved Domains (4) summary

cd01390
Location:713 → 764

HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

pfam00505
Location:782 → 849

HMG_box; HMG (high mobility group) box

pfam01342
Location:617 → 689

SAND; SAND domain

pfam03172
Location:49 → 147

HSR; HSR domain
XM_015111307.2 → XP_014966793.1 nuclear autoantigen Sp-100 isoform X5

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (5) summary

cd05501
Location:767 → 868

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:698 → 739

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:594 → 669

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain

cl00748
Location:529 → 598

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111309.2 → XP_014966795.1 nuclear autoantigen Sp-100 isoform X7

UniProtKB/TrEMBL

A0A1D5R4K1

Conserved Domains (5) summary

cd05501
Location:762 → 863

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:693 → 734

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:589 → 664

SAND; SAND domain

pfam03172
Location:27 → 121

Sp100; Sp100 domain

cl00748
Location:524 → 593

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111308.2 → XP_014966794.1 nuclear autoantigen Sp-100 isoform X6

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (5) summary

cd05501
Location:764 → 865

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:695 → 736

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:591 → 666

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain

cl00748
Location:526 → 595

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...
XM_015111313.2 → XP_014966799.1 nuclear autoantigen Sp-100 isoform X10

UniProtKB/TrEMBL

H9ZCQ7

Conserved Domains (4) summary

cd05501
Location:744 → 845

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:675 → 716

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:571 → 646

SAND; SAND domain

pfam03172
Location:52 → 146

Sp100; Sp100 domain
XM_001112681.4 → XP_001112681.4 nuclear autoantigen Sp-100 isoform X8

UniProtKB/TrEMBL

A0A1D5Q7N7

Conserved Domains (4) summary

cd01390
Location:690 → 741

HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

pfam00505
Location:759 → 826

HMG_box; HMG (high mobility group) box

pfam01342
Location:594 → 666

SAND; SAND domain

pfam03172
Location:49 → 147

HSR; HSR domain
XM_028831199.1 → XP_028687032.1 nuclear autoantigen Sp-100 isoform X11

Conserved Domains (1) summary

pfam03172
Location:24 → 122

HSR; HSR domain
XM_015111311.2 → XP_014966797.1 nuclear autoantigen Sp-100 isoform X9

UniProtKB/TrEMBL

A0A1D5R4K1

Related

ENSMMUP00000050658.2, ENSMMUT00000077493.2

Conserved Domains (5) summary

cd05501
Location:751 → 852

Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...

cd15541
Location:682 → 723

PHD_TIF1_like; PHD finger found in the transcriptional intermediary factor 1 (TIF1) family and similar proteins

pfam01342
Location:578 → 653

SAND; SAND domain

pfam03172
Location:16 → 110

Sp100; Sp100 domain

cl00748
Location:513 → 582

Ribosomal_L32_L32e; Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the ...