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    PLCB3 phospholipase C beta 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717764, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLCB3provided by VGNC
    Official Full Name
    phospholipase C beta 3provided by VGNC
    Primary source
    VGNC:VGNC:76165
    See related
    Ensembl:ENSMMUG00000012948
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLCB3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (10274345..10292537, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (10258430..10276612, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene catsper channel auxiliary subunit zeta Neighboring gene G protein-coupled receptor 137 Neighboring gene BCL2 associated agonist of cell death Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14B Neighboring gene FKBP prolyl isomerase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
    Names
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3
    phospholipase C, beta 3 (phosphatidylinositol-specific)
    XP_014969380.2
    XP_014969381.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      10274345..10292537 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015113895.2 → XP_014969381.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

      UniProtKB/TrEMBL
      G7NCJ0
      Conserved Domains (7) summary
      cd00275
      Location:728 → 843
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:316 → 693
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      PRK06975
      Location:905 → 1066
      PRK06975; bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
      cd13361
      Location:22 → 149
      PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
      pfam08703
      Location:1029 → 1202
      PLC-beta_C; PLC-beta C terminal
      cd16210
      Location:154 → 304
      EFh_PI-PLCbeta3; EF-hand motif found in phosphoinositide phospholipase C beta 3 (PI-PLC-beta3)
      pfam06631
      Location:951 → 988
      DUF1154; Protein of unknown function (DUF1154)

    2. XM_015113894.2 → XP_014969380.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

      UniProtKB/TrEMBL
      G7NCJ0
      Related
      ENSMMUP00000016999.4, ENSMMUT00000018158.4
      Conserved Domains (7) summary
      cd00275
      Location:728 → 843
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:316 → 693
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      PRK06975
      Location:905 → 1066
      PRK06975; bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
      cd13361
      Location:22 → 149
      PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
      pfam08703
      Location:1029 → 1202
      PLC-beta_C; PLC-beta C terminal
      cd16210
      Location:154 → 304
      EFh_PI-PLCbeta3; EF-hand motif found in phosphoinositide phospholipase C beta 3 (PI-PLC-beta3)
      pfam06631
      Location:951 → 988
      DUF1154; Protein of unknown function (DUF1154)
    Nucleotide Protein
    Heading Accession and Version

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