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    DEGS1 delta 4-desaturase, sphingolipid 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702128, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DEGS1provided by VGNC
    Official Full Name
    delta 4-desaturase, sphingolipid 1provided by VGNC
    Primary source
    VGNC:VGNC:71620
    See related
    Ensembl:ENSMMUG00000002400
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DEGS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (81638838..81648960)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (142241073..142250552, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene F-box protein 28 Neighboring gene uncharacterized LOC106993365 Neighboring gene nuclear VCP like Neighboring gene microRNA mir-320b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingolipid delta-4 desaturase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingolipid delta(4)-desaturase DES1
    Names
    degenerative spermatocyte homolog 1, lipid desaturase
    NP_001252935.1
    XP_028693334.1
    XP_028693362.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266006.1 → NP_001252935.1  sphingolipid delta(4)-desaturase DES1

      See identical proteins and their annotated locations for NP_001252935.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045802
      UniProtKB/TrEMBL
      F6PPX9, G7MEG8
      Related
      ENSMMUP00000003220.2, ENSMMUT00000003410.4
      Conserved Domains (3) summary
      PLN02579
      Location:5 → 314
      PLN02579; sphingolipid delta-4 desaturase
      cd03508
      Location:26 → 315
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
      pfam08557
      Location:6 → 42
      Lipid_DES; Sphingolipid Delta4-desaturase (DES)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      81638838..81648960
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028837501.1 → XP_028693334.1  sphingolipid delta(4)-desaturase DES1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZM44, G7MEG8
      Related
      ENSMMUP00000065685.1, ENSMMUT00000104847.1
      Conserved Domains (1) summary
      cd03508
      Location:17 → 304
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

    2. XM_028837529.1 → XP_028693362.1  sphingolipid delta(4)-desaturase DES1 isoform X2

      UniProtKB/TrEMBL
      G7MEG8
      Conserved Domains (1) summary
      cd03508
      Location:1 → 279
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    Nucleotide Protein
    Heading Accession and Version

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