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    ORAI2 ORAI calcium release-activated calcium modulator 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714917, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ORAI2provided by VGNC
    Official Full Name
    ORAI calcium release-activated calcium modulator 2provided by VGNC
    Primary source
    VGNC:VGNC:75665
    Locus tag
    EGK_13568
    See related
    Ensembl:ENSMMUG00000012024
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ORAI2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (44551855..44571278)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (127830004..127846759)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene SH2B adaptor protein 2 Neighboring gene PRKR interacting protein 1 Neighboring gene alkB homolog 4, lysine demethylase Neighboring gene leucine rich repeats and WD repeat domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables store-operated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in store-operated calcium entry IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein orai-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265868.1 → NP_001252797.1  protein orai-2

      See identical proteins and their annotated locations for NP_001252797.1

      Status: PROVISIONAL

      Source sequence(s)
      JU472743
      UniProtKB/TrEMBL
      A0A1D5R3E4, A0A8J8XPU5, G7MNX7, H9G037
      Conserved Domains (1) summary
      pfam07856
      Location:47 → 228
      Orai-1; Mediator of CRAC channel activity

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      44551855..44571278
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845039.1 → XP_028700872.1  protein orai-2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RA22, F7GY76, H9G037
      Related
      ENSMMUP00000072332.1, ENSMMUT00000086928.1
      Conserved Domains (1) summary
      pfam07856
      Location:54 → 235
      Orai-1; Mediator of CRAC channel activity

    2. XM_015134538.2 → XP_014990024.1  protein orai-2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5R3E4, A0A8J8XPU5, G7MNX7, H9G037
      Related
      ENSMMUP00000054830.1, ENSMMUT00000062516.2
      Conserved Domains (1) summary
      pfam07856
      Location:47 → 228
      Orai-1; Mediator of CRAC channel activity

    3. XM_028845040.1 → XP_028700873.1  protein orai-2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RA22, F7GY76, H9G037
      Conserved Domains (1) summary
      pfam07856
      Location:54 → 235
      Orai-1; Mediator of CRAC channel activity
    Nucleotide Protein
    Heading Accession and Version

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