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    TRIM15 tripartite motif containing 15 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712497, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TRIM15provided by VGNC
    Official Full Name
    tripartite motif containing 15provided by VGNC
    Primary source
    VGNC:VGNC:83958
    See related
    Ensembl:ENSMMUG00000002890
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM15 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (139725926..139734557, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (30863199..30871850)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 26 Neighboring gene HLA class I histocompatibility antigen, B-37 alpha chain-like Neighboring gene polyadenylate-binding protein-interacting protein 1 pseudogene Neighboring gene tripartite motif containing 10 Neighboring gene tripartite motif containing 40

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic evolution of MHC class I region in primates. Fukami-Kobayashi K, et al. Proc Natl Acad Sci U S A, 2005 Jun 28. PMID 15967992, Free PMC Article
    2. Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex. Kulski JK, et al. Mol Biol Evol, 2004 Nov. PMID 15269276
    3. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. Shiina T, et al. Genetics, 2006 Jul. PMID 16702430, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM15
    Names
    tripartite motif protein 15
    tripartite motif-containing protein 15
    NP_001108420.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114948.1 → NP_001108420.1  E3 ubiquitin-protein ligase TRIM15

      See identical proteins and their annotated locations for NP_001108420.1

      Status: PROVISIONAL

      Source sequence(s)
      AB128049
      UniProtKB/Swiss-Prot
      Q5TM55
      UniProtKB/TrEMBL
      G7MRE6
      Related
      ENSMMUP00000003861.2, ENSMMUT00000004092.3
      Conserved Domains (5) summary
      smart00336
      Location:80 → 119
      BBOX; B-Box-type zinc finger
      pfam09088
      Location:252 → 327
      MIF4G_like; MIF4G like
      cd15826
      Location:295 → 464
      SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
      cl17238
      Location:16 → 60
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl23765
      Location:130 → 184
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      139725926..139734557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5TM55.1 GenPept UniProtKB/Swiss-Prot:Q5TM55

    Gene LinkOut

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    Research Materials