ITM2B integral membrane protein 2B [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ITM2Bprovided by VGNC
Official Full Name: integral membrane protein 2Bprovided by VGNC
Primary source: VGNC:VGNC:73799
See related: Ensembl:ENSMMUG00000007888
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	17	NC_041770.1 (26654777..26683707)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	17	NC_027909.1 (27397334..27426269)

Chromosome 17 - NC_041770.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH44780 (e-PCR)
- UniSTS:57353

D13S1155 (e-PCR)
- UniSTS:4891

A002O26 (e-PCR)
- UniSTS:64356

SHGC-34192 (e-PCR)
- UniSTS:450

RH44653 (e-PCR)
- UniSTS:64709

D13S841E (e-PCR)
- UniSTS:151516

D13S864E (e-PCR)
- UniSTS:151526

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables amyloid-beta binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of amyloid precursor protein biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular exosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: integral membrane protein 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001258055.1 → NP_001244984.1 integral membrane protein 2B

See identical proteins and their annotated locations for NP_001244984.1

Status: PROVISIONAL

Source sequence(s)

JU477907

UniProtKB/TrEMBL

F7B0D0, G7NK44

Related

ENSMMUP00000010359.2, ENSMMUT00000011048.4

Conserved Domains (1) summary

smart01039
Location:137 → 231

BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer